Newly-generated cells may lead to a deeper understanding of bile duct disease and be a powerful tool for finding new treatments.
Researchers have engineered a new method to improve the survival and potency of cell transplants to treat diabetes.
Computational biology study found two fundamental mechanisms involved in the cell play important roles and may help better control cells used in regenerative medicine applications
Researchers say the findings lay groundwork that could lead to methods for expanding stem cell numbers from donated cord blood biobanks to improve availability for people with leukemia.
Thanks to funding from Medicine by Design, a University of Toronto scientist and her team are closer to finding a way to protect the brain from damage for children who must be treated with cranial radiation.
Using state-of-the art sequencing technology, Medicine by Design-funded scientists have revealed how stem cells are able to generate new blood cells throughout our life, and how these same cellular mechanisms can evade chemotherapy to survive and cause relapse many years later.
Scientists can now select individual cells from their local environment & study their molecular contents. The new tool will enable a deeper study of stem cells and other rare cell types for diagnostics & therapy.
New version is more stable than the protein that occurs in nature, and could lead to new treatments for reversing nerve damage caused by traumatic injury or stroke.
The technique could point the way toward new treatments with the potential to reverse forms of vision loss that are currently incurable.
Data generation, evidence of clinical effectiveness, cost and social values among the key considerations
Cross-species study shows that Type 2 diabetes drug metformin could change the way childhood brain injury is treated
Discovery to provide insights into liver development and disease progression
A team of researchers led by scientists at the University of Toronto has delayed the onset of amyotrophic lateral sclerosis (ALS) in mice. They are cautiously optimistic that this research, which was funded in part by a Medicine by Design 2018 New Ideas Award, combined with other clinical advances, points to a potential treatment for ALS in humans.
Scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease.
'We think we can really accelerate the field and its capacity to improve lives'
