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SUMMARY:Conversations in Convergence: Omar F. Khan\, PhD\, and Tharini Sivasubramaniyam\, PhD
DESCRIPTION:Join us for our Conversations in Convergence series which is an interactive discussions between Medicine by Design researchers who study similar questions using different approaches. \nThe goal is to foster cross-disciplinary discussions in support of convergence\, which is the integration of approaches from engineering\, science\, medicine and other fields to expand knowledge and spark innovation. The researchers will discuss how their unique perspectives\, knowledge and ideas inform their work\, and how their diverse approaches intersect and complement one another to advance regenerative medicine. \nOur speakers will be: \n\nOmar F. Khan\, PhD – Assistant Professor\, Institute of Biomedical Engineering and Department of Immunology\, University of Toronto and Medicine by Design\, Investigator\nTharini Sivasubramaniyam\, PhD –Post-Doctoral Fellow\, Clinton Robbins Lab\, Toronto General Hospital Research Institute\, University Health Network\n\nRegister now\n \nProfessor Khan earned his B.A.Sc. and Ph.D. in Chemical Engineering and Applied Chemistry from the University of Toronto\, and his academic supervisor was Professor Michael V. Sefton. He later joined the laboratories of Professors Daniel G. Anderson and Robert Langer as a Postdoctoral Associate in the Massachusetts Institute of Technology. Professor Khan is also the Scientific Founder and former Chief Scientist of Tiba Biotech\, a Boston-area company spun out from his postdoctoral research. As an mRNA nanotechnology and vaccine expert\, he is regularly featured in television\, radio and print news. His early career focused on the creation of three dimensional organoid models and engineered tissue substitutes. This work evolved to include the development of nucleic acid-based platform technologies and novel biomaterials to study the genetic mechanisms of diseases and create RNA-based therapies. Now\, Professor Khan endeavors to contribute to Canada’s growing research-to-translation ecosystem by creating new regenerative medicine-enabling technologies\, and training highly qualified personnel capable of addressing diverse local and global bioengineering needs. \n  \nTharini completed her BSc\, MSc and PhD at University of Toronto. Her MSc was under the supervision of Dr. Isabella Caniggia where she assessed the role of Par6\, a key regulator of cell polarity\, during normal human placental development and in preeclampsia. She shifted gears and went on and completed her PhD under Dr. Minna Woo where she investigated how hepatic signaling affects atherosclerosis in vivo. During this time\, she was the recipient of many prestigious awards including Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Award\, Canadian Liver Foundation Graduate Studentship\, and Canadian Diabetes Association Doctoral Student Research Award. Wanting to broaden her knowledge in immunology she joined the laboratory of Dr. Clinton Robbins as a postdoctoral fellow where she is tackling major unmet biomedical questions in understanding how tissue microenvironments affect the function of immune cells.
URL:https://mbd.ccrm.ca/event/conversations-in-convergence-omar-khan-phd-and-thara-sivasubramaniyam-phd/
CATEGORIES:Other Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20211104T130000
DTEND;TZID=America/Toronto:20211104T143000
DTSTAMP:20260405T185234
CREATED:20211014T134705Z
LAST-MODIFIED:20211014T160422Z
UID:15372-1636030800-1636036200@mbd.ccrm.ca
SUMMARY:Program Information Session: Building a Biotech Venture
DESCRIPTION:Join us on November 4th for an information session to learn about the Building a Biotech Venture Program.\nRegister for info session\nTake your first steps toward entrepreneurship with the Building a Biotech Venture program\, a program for trainees who are doing regenerative medicine- or precision medicine-related research in labs at the University of Toronto or its affiliated hospitals. \nThis year\, Medicine by Design is offering this program in partnership with Precision Medicine Initiative (PRiME) as well as our foundational partners the Health Innovation Hub (H2i)\, a campus-linked accelerator at the Temerty Faculty of Medicine; and Talk Boutique. \nThrough a series of workshops over winter/spring 2022\, teams will:\n\nLearn how to think about their research in terms of a product or business;\nBuild a business canvas and develop their product or venture concept;\nReceive guidance from industry experts on intellectual property\, clinical translation\, and early-stage stage investment.\nCreate a pitch deck and receive coaching on telling their venture story; and\nReceive regular mentoring from entrepreneurs throughout the process.\n\nThe program will culminate in a pitch competition in May\, where the first-place team will receive $25\,000 and the second-place team will receive $10\,000 in research funding to advance their product concept.Click here to read about HDAX Therapeutics\, the team who received research funding as the winner of last year’s pitch competition. \nTo learn more about the program and how to apply\, please join us virtually on November 4\, 2021\, from 1 p.m. to 2:30 p.m. EST for an information session. This session will provide an overview of the program and how to apply\, as well as an introduction to H2i’s 10-point plan\, which outlines 10 key elements of a business canvas. \nClick here to read about HDAX Therapeutics\, the team who received research funding as the winner of last year’s pitch competition. \nIf you have any immediate questions regarding this program\, please contact Stephanie Hume (stephanie.hume@utoronto.ca). \nThis program will be offered virtually.\n \n\nBuilding a Biotech Venture program breakdown:\n\n\nPhase 1: Program Information Session and Team Building \nNovember 4\, 1 p.m. to 2:30 p.m.\nThis session will provide an overview of the program and how to fill out the business one-pager\, which is required to enroll\, as well as an introduction to H2i’s 10-point plan\, which outlines 10 key elements of a business canvas.\n\nThis session will be followed by a team building session the week of November 15 for trainees to build or add expertise to their teams. Stay tuned for more details. \n*Phase 1 of the program will be open to all trainees within the Medicine by Design and PRiME communities. \n\nPhase 2: Venture Development Workshops\nJanuary-April 2022\n\nThe program will include workshops run by industry experts to help in scaling their ventures and prepare them for the pitch competition. The program will include workshops run by industry experts to help teams in scaling their ventures and prepare them for the pitch competition. \n-Workshop 1: Mentor introduction Event (January)\n-Workshop 2: Intellectual property (February)\n-Workshop 3: Clinical translation and regulatory affairs (March)\n-Workshop 4:  De-mystifying the pathway through to early-stage investment (March)\n-Workshop 5: Pitching and presentation skills workshop (April) \n*To apply to phase 2\, teams must submit a one-page business canvas outlining their venture concept. Proposed product or venture concept must have an application to regenerative or precision medicine. Application documents to be provided post information session.  \n*Each team must have at least one team member who’s current supervisor has a faculty appointment at U of T to be eligible for Phase 2. \n\nSession 3: Medicine by Design Pitch Competition\nMay 2022\nSelect teams will pitch for a chance to receive $25\,000 (first place) or $10\,000 (second place) in research funding.
URL:https://mbd.ccrm.ca/event/biotech-venture-2021-info-session/
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20211028T113000
DTEND;TZID=America/Toronto:20211028T123000
DTSTAMP:20260405T185234
CREATED:20211021T190020Z
LAST-MODIFIED:20211021T191214Z
UID:15649-1635420600-1635424200@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/adipose-biology-seminar-series-12/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20211026T120000
DTEND;TZID=America/Toronto:20211026T130000
DTSTAMP:20260405T185234
CREATED:20211021T175547Z
LAST-MODIFIED:20211021T175719Z
UID:15628-1635249600-1635253200@mbd.ccrm.ca
SUMMARY:Adipose Biology Seminar Series
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/adipose-biology-seminar-series-2/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20211025T140000
DTEND;TZID=America/Toronto:20211025T150000
DTSTAMP:20260405T185234
CREATED:20211021T190402Z
LAST-MODIFIED:20211021T190402Z
UID:15652-1635170400-1635174000@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-4/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20211019T120000
DTEND;TZID=America/Toronto:20211019T130000
DTSTAMP:20260405T185234
CREATED:20210729T141125Z
LAST-MODIFIED:20210804T141519Z
UID:14762-1634644800-1634648400@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Wilson Wong\, PhD - Boston University
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Wilson Wong\, PhD\, Associate Professor in the Department of Biomedical Engineering at Boston University. \nThe title of this talk will be\, Mammalian Cell Design Using Synthetic Biology \n Register for this virtual event. \n \nMore About WILSON WONG:\nWilson Wong is an Associate Professor in the Biomedical Engineering Department at Boston University\, and a core member of the BU Biological Design Center. His lab is focused on developing synthetic biology tools in mammalian systems for cell-based immunotherapy. He received his B.S. degree in Chemical Engineering from UC Berkeley and a Ph.D. degree in Chemical Engineering from UCLA under the guidance from Dr. James Liao. He did his postdoctoral work with Dr. Wendell Lim and Arthur Weiss at UCSF. He is the recipient of the NIH Director’s New Innovator and NSF CAREER Award. \n Learn more about Wilson Wong’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-wilson-wong-phd-boston-university/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210921T120000
DTEND;TZID=America/Toronto:20210921T130000
DTSTAMP:20260405T185234
CREATED:20210728T195206Z
LAST-MODIFIED:20210831T134648Z
UID:14756-1632225600-1632229200@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Dale Greiner\, PhD - University of Massachusetts Medical School
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Dale Greiner\, PhD\, Professor of Molecular Medicine and Co-Director of the Diabetes Center of Excellence at University of Massachusetts Medical School. \nThe title of this talk will be\, TBC \n Register for this virtual event. \n \nMore About DALE GREINER:\nDr. Greiner is nationally and internationally recognized for pioneering the development and use of mice engrafted with functional human cells and tissues. This work has generated high interest in the biomedical research community for use as a preclinical model for the investigation of human diabetes\, cancer\, infectious disease\, regenerative medicine and autoimmunity. The unique animal model allows Dr. Greiner and his team to investigate autoimmune type 1 diabetes and the cells that regulate immune responses in humans. \nHe currently serves as Vice Chair of the Institutional Animal Care and Use Committee and member of the Diabetes Research Center Executive Committee and the Flow Cytometry Advisory Committee. Over the past four decades\, he has co-authored more than 300 publications in the research specialization areas of Immunology\, Transplantation\, Autoimmunity\, and Diabetes. \nDr. Greiner has served as a regular member of the National Institutes of Health Immunology Sciences Study Section and the Hypersensitivity\, Autoimmune\, and Immune-mediated Diseases Study Section. He has also served as Chair of the Veterans Administration Immunology Review Subcommittee B and Chair of many ad hoc NIH and JDRF study sections. In addition\, he has served as Chair of the Medical Science Review Committee for the Juvenile Diabetes Research Foundation\, Chairman of the American Diabetes Association Scientific Sessions Committee\, as well as Program Chair and Council Chair of the American Diabetes Association Council on Immunology\, Immunogenetics and Transplantation. \nThe recipient of numerous awards for his research\, Dr. Greiner has received the A.J. Julian Scholarship for Academic Excellence\, the Basil O’Connor Scholar Research Award from the March of Dimes\, and the Kayla and Gerald Grodsky and the David Rumbough Awards from the Juvenile Diabetes Research Foundation\, Int. \n Learn more about Dale Greiner’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-dale-greiner-phd-university-of-massachusetts-medical-school/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210830T160000
DTEND;TZID=America/Toronto:20210830T170000
DTSTAMP:20260405T185234
CREATED:20210728T153237Z
LAST-MODIFIED:20210728T193612Z
UID:14747-1630339200-1630342800@mbd.ccrm.ca
SUMMARY:Careers by Design: Building a Professional Development Blueprint
DESCRIPTION:Register now for the last session of Careers by Design: Building a Professional Development Blueprint\, hosted by Medicine by Design’s Healthy and Inclusive Labs Committee. The series continues on Monday\, August 30 from 4 p.m. to 5 p.m. \nThis six-part workshop series and the Individual Development Plan (IDP) aim to foster healthy lab environments that support the inclusion and well-being of all members\, while empowering graduate students\, post-doctoral fellows and research/scientific associates to realize their academic and professional goals. All workshops will be led by Nana Lee\, PhD\, Director\, Graduate Professional Development & Mentorship\, and Assistant Professor in the departments of Biochemistry & Immunology at the University of Toronto. \nMonday\, August 30 – Implementation and Feedback on Job Applications \nThis will be an interactive workshop where participants will receive peer feedback\, guided by the instructor\, on their job applications to any career of their choice and a big picture review of workshops I-IV to strategically move forward in their professional and career development. \nIf you missed any of the previous sessions\, you can still participate in the workshop series. The recordings from previous workshops can be viewed by using the links provided below. \nRegister for this virtual event\n*This is the last workshop of this series.  \nThis series is for trainees in past and/or current Medicine by Design-funded labs. \nIf you have any immediate questions regarding this program\, please contact us at info.mbd@utoronto.ca. \n\nWorkshop schedule:\n*All workshops will take place from 4 p.m. to 5 p.m. \n\n\nWorkshop 1: Monday\, March 29 – Recording available\nIndividual Development Plans Intro – Optimizing Research Productivity and Professional Development \nAt the end of this workshop\, both faculty and mentees (students and postdocs) will have an understanding of how to effectively use the AAAS individual development plan to plan SMART (Specific\, Measurable\, Attainable\, Relevant\, Time-bound) goals in research productivity and career development while using the tool for optimal mentorship. \n\n\nWorkshop 2: Monday\, April 26 –Recording available\nCreating Your Individual Development Plans \nLearners will be given peer and instructor-led feedback on best avenues to attain their SMART goals and an overview of the multiple career options available for them. \n\n\nWorkshop 3: Monday\, May 31 –\nRecording available\nMeaningful Engagement \nParticipants will gain an understanding of introductory design-thinking principles to brainstorm their wayfinding purpose compass around what they love\, are good at and care about. We will also discuss specific action items for learners to help make their dream purpose a reality. \n\n\nWorkshop 4: Monday\, June 28 – Recording available\n\nTelling your story through your interview\, cover letter and CV \nAt the end of this workshop\, trainees will understand the difference between an academic and non-academic job application (CV vs resume)\, how to write the stellar cover letter\, and gain tips on interviewing and a LinkedIn presence. \n\n\nWorkshop 5: Monday\, July 26 –\nRecording available soon\nWellness and Equity Diversity and Inclusion in Professional and Career Development \nThe goal of this workshop is to introduce or re-emphasize the concepts of an equity-minded scholar\, allyship and wellness issues and how to bring these concepts into daily practice as a graduate student\, postdoctoral fellow or faculty member towards any career. \n\n\nWorkshop 6: Monday\, August 30 – NEXT Session\nImplementation and Feedback on Job Applications \nAt the end of this workshop\, trainees will receive peer feedback (guided by the instructor) on their job applications to any career of their choice and a big picture review of workshops I-IV to strategically move forward in their professional and career development.
URL:https://mbd.ccrm.ca/event/careers-by-design-building-a-professional-development-blueprint-3/
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20210825
DTEND;VALUE=DATE:20210828
DTSTAMP:20260405T185234
CREATED:20210727T172036Z
LAST-MODIFIED:20210803T153838Z
UID:14739-1629849600-1630108799@mbd.ccrm.ca
SUMMARY:Human Cell Atlas – Developmental and Pediatric Cell Atlas Meeting
DESCRIPTION:This HCA meeting will focus on creating maps of healthy human development and pediatric tissues. The goal is to energize and bring together multiple communities to develop the human development and pediatric atlas projects. \nThe HCA is  specifically interested in engaging developmental biologists; embryologists; clinicians focusing on development and pediatrics; those working on technology and models useful for studying development\, including imaging and single-cell technologies; computational biologists and ethicists. \nRead more about the meeting and register here.
URL:https://mbd.ccrm.ca/event/human-cell-atlas-developmental-and-pediatric-cell-atlas-meeting/
CATEGORIES:Medicine by Design Sponsored Event
ORGANIZER;CN="Human Cell Atlas":MAILTO:hca@humancellatalas.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210726T160000
DTEND;TZID=America/Toronto:20210726T170000
DTSTAMP:20260405T185234
CREATED:20210526T173601Z
LAST-MODIFIED:20210723T183633Z
UID:14185-1627315200-1627318800@mbd.ccrm.ca
SUMMARY:Careers by Design: Building a Professional Development Blueprint
DESCRIPTION:Register now for new sessions of Careers by Design: Building a Professional Development Blueprint\, hosted by Medicine by Design’s Healthy and Inclusive Labs Committee. The series continues on Monday\, July 26 from 4 p.m. to 5 p.m. \nThis six-part workshop series and the Individual Development Plan (IDP) aim to foster healthy lab environments that support the inclusion and well-being of all members\, while empowering graduate students\, post-doctoral fellows and research/scientific associates to realize their academic and professional goals. All workshops will be led by Nana Lee\, PhD\, Director\, Graduate Professional Development & Mentorship\, and Assistant Professor in the departments of Biochemistry & Immunology at the University of Toronto. \nMonday\, July 26 – Wellness and Equity Diversity and Inclusion in Professional and Career Development \nThrough this workshop the goal is to introduce or re-emphasize the concepts of an equity-minded scholar\, allyship and wellness issues and how to bring these concepts into daily practice as a graduate student\, postdoctoral fellow or faculty member towards any career. \nIf you missed any of the previous sessions\, you can still participate in the workshop series. The recordings from previous workshops can be viewed by using the links provided below. \nRegister for this virtual event\n*Once registered\, you will be automatically enrolled in the remaining workshops.  \nThis series is for trainees in past and/or current Medicine by Design-funded labs. \nIf you have any immediate questions regarding this program\, please contact us at info.mbd@utoronto.ca. \n\nWorkshop schedule:\n*All workshops will take place from 4 p.m. to 5 p.m. \n\n\nWorkshop 1: Monday\, March 29 – Recording available\nIndividual Development Plans Intro – Optimizing Research Productivity and Professional Development \nAt the end of this workshop\, both faculty and mentees (students and postdocs) will have an understanding of how to effectively use the AAAS individual development plan to plan SMART (Specific\, Measurable\, Attainable\, Relevant\, Time-bound) goals in research productivity and career development while using the tool for optimal mentorship. \n\n\nWorkshop 2: Monday\, April 26 –Recording available\nCreating Your Individual Development Plans \nLearners will be given peer and instructor-led feedback on best avenues to attain their SMART goals and an overview of the multiple career options available for them. \n\n\nWorkshop 3: Monday\, May 31 –\nRecording available\nMeaningful Engagement \nParticipants will gain an understanding of introductory design-thinking principles to brainstorm their wayfinding purpose compass around what they love\, are good at and care about. We will also discuss specific action items for learners to help make their dream purpose a reality. \n\n\nWorkshop 4: Monday\, June 28 – Recording available\n\nTelling your story through your interview\, cover letter and CV \nAt the end of this workshop\, trainees will understand the difference between an academic and non-academic job application (CV vs resume)\, how to write the stellar cover letter\, and gain tips on interviewing and a LinkedIn presence. \n\n\nWorkshop 5: Monday\, July 26 –\nNEXT Session\nWellness and Equity Diversity and Inclusion in Professional and Career Development \nThe goal of this workshop is to introduce or re-emphasize the concepts of an equity-minded scholar\, allyship and wellness issues and how to bring these concepts into daily practice as a graduate student\, postdoctoral fellow or faculty member towards any career. \n\n\nWorkshop 6: Monday\, August 30\nImplementation/Feedback on Job Applications \nAt the end of this workshop\, trainees will receive peer feedback (guided by the instructor) on their job applications to any career of their choice and a big picture review of workshops I-IV to strategically move forward in their professional and career development.
URL:https://mbd.ccrm.ca/event/careers-by-design-building-a-professional-development-blueprint-2/
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210721T130000
DTEND;TZID=America/Toronto:20210721T150000
DTSTAMP:20260405T185234
CREATED:20210625T152034Z
LAST-MODIFIED:20210720T142959Z
UID:14412-1626872400-1626879600@mbd.ccrm.ca
SUMMARY:Cell and Gene Therapies Innovations Showcase
DESCRIPTION:Join us for the Cell and Gene Therapies Innovations Showcase\, hosted by Medicine by Design and the Precision Medicine Initiative (PRiME). This two-day event will highlight cell and gene therapy strategies and enabling technologies from both academia and industry in the Canadian ecosystem. \nThis event features talks from world renowned researchers from the University of Toronto and its affiliated hospitals\, industry leaders and exceptional trainees who represent the next generation of trailblazing scientists in the field of regenerative and precision cell-based medicines. \nRegister now for session 2 \n\nDay 1 – Cell and Gene Therapies\nThursday\, July 15\, 1 p.m. to 3 p.m. – Recording Now Available\nView Day 1 Agenda \nModerator: Michael Sefton\, Executive Director\, Medicine by Design \nOpening Remarks – 1:00pm: Michael Sefton\, Executive Director\, Medicine by Design \nGroup 1 Presenters – 1:05pm-1:55pm\nShreya Shukla – Co-Founder and Director\, Research\, Notch Therapeutics\nShinichiro Ogawa – Affiliate Scientist\, McEwen Stem Cell Institute\, University Health Network\nQuinn Matthews – Master’s Student\, Keith Pardee Lab\, Leslie Dan Faculty of Pharmacy\, University of Toronto\nDaniel Wang – PhD Student\, Shana Kelley Lab\, Leslie Dan Faculty of Pharmacy\, University of Toronto \nPanel Discussion with Group 1 – 1:55pm-2:05pm: Moderated by Michael Sefton \nGroup 2 Presenters -2:10pm-2:50pm\nAndras Nagy – Founder and Director\, panCELLa\nMaryam Faiz – Assistant Professor\, Department of Surgery\, University of Toronto\nChristoph Haller – Cardiovascular Surgeon\, The Hospital for Sick Children and PhD Candidate\, Michael Laflamme Lab\, McEwen Stem Cell Institute\, University Health Network \nPanel Discussion with Group 2 – 2:50pm-3:00pm: Moderated by Michael Sefton \nClosing Remarks – 3:00pm \n\nAcademic Researchers\nMaryam\nFaizShinichiro Ogawa Christoph\nHallerQuinn\nMatthewsDaniel\nWangMaryam\nFaiz \n \nAssistant Professor\, Department of Surgery\, University of Toronto\nMaryam Faiz received her PhD from the Autonomous University of Barcelona in Spain. She trained with  Milos Pekny at the University of Goteborg in Sweden\, and then with Dr. Andras Nagy at the Lunenfeld-Tanenbaum Research Institute in Toronto. Faiz is interested in uncovering new treatments for brain injury and disease. Her lab is interested in the roles of astrocytes in the injured/diseased brain\, and how this knowledge can inform future therapeutic interventions. One exciting area of research she is currently pursuing is the direct lineage reprogramming of astrocytes to neurons and oligodendrocytes. She believes that the ability to create bespoke cell types\, at the source of injury or disease may revolutionize the next generation of CNS therapeutics. \nShinichiro Ogawa  \nAffiliate Scientist\, McEwen Stem Cell Institute\, University Health Network\n \nShinichiro Ogawa is an Affiliate Scientist at the McEwen Stem Cell Institute (MSCI) with a cross-appointment at the Multi-Organ Transplant Program at UHN and is an Assistant Professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. As a trained clinician and hepato-biliary\, liver transplant surgeon in Japan\, he is also appointed as a Professor of Surgery at the Shinshu University School of Medicine in Japan. His research work focuses on using stem cell biology to generate functional hepatocytes and cholangiocytes from human pluripotent stem cells with the long-term goal of developing targeted cell therapies for liver disease.   \n Ogawa obtained his MD at the Tokyo Medical University in 1994 and his PhD at the Shinshu University School of Medicine in 2005 in Japan. Ogawa continued his training as a postdoctoral fellow and subsequently as a Scientific Associate under Gordon Keller before starting his independent research program in April 2019.   \nSince joining the Keller laboratory\, Ogawa has made significant progress in advancing the field of liver regenerative medicine. He has successfully developed a method to generate functional liver cells—hepatocytes\, and cholangiocytes—from human pluripotent stem cells\, which is a remarkable accomplishment. In his independent research\, he will continue this outstanding trajectory by evaluating the optimal graft composition of these cells for treating different forms of liver failure in pre-clinical transplantation studies\, and further elucidate the drivers of hepatic lineage development in pluripotent stem cells. In parallel\, he will continue developing a methodology to produce an unlimited supply of human liver cells and to develop novel cell therapies for liver diseases.  \n  \nChristoph\nHaller \nCardiovascular Surgeon\, Division of Cardiovascular Surgery\, The Labatt Family Heart Centre\, The Hospital for Sick Children and PhD Candidate\, Michael Laflamme Lab\, Department of Laboratory Medicine & Pathobiology\, Institute of Biomedical Engineering\, McEwen Stem Cell Institute\, University Health Network\n \nDr. Christoph Haller graduated from Albert-Ludwigs University Freiburg\, Germany and completed his cardiac surgery training in the Department of Cardiovascular Surgery at the University Hospital Freiburg\, Germany\, and the Department of Thoracic and Cardiovascular Surgery at the University Hospital Tuebingen\, Germany. Early in his career\, he subspecialized in congenital heart surgery and completed clinical and research fellowships at the Hospital for Sick Children\, University of Toronto.   \nHis practice is focused on open heart surgery in neonates and infants and adult congenital heart disease\, covering the spectrum of congenital heart disease from single ventricle palliation to mechanical support and heart transplantation. He is leading the minimally invasive congenital heart surgery program at SickKids. Dr. Haller’s academic interests are focused on the preservation\, recovery\, and regeneration of cardiac function. He is applying stem cell therapy\, mechanical circulatory support\, and new imaging technologies in various translational fetal\, pediatric and adult research models to investigate mechanisms of heart failure and therapeutic strategies to preserve or restore function. Dr. Haller is further exploring extrauterine fetal support commonly referred to as artificial placenta to lower morbidity and mortality in extremely premature neonates and to apply innovative therapeutic approaches to this most fragile group of patients.  \n  \nQuinn\nMatthews \nMaster’s Student\, Keith Pardee Lab\, Leslie Dan Faculty of Pharmacy\, University of Toronto \nOriginally from Vancouver\, Quinn joined Professor Keith Pardee’s research group as a MSc student in 2019. He’s passionate about de-centralizing science/healthcare\, and is involved in a few projects within the lab that aim to solve real-life problems using synthetic biology.   \n  \n  \n  \nDaniel\nWang \nPhD Student\, Shana Kelley Lab\, Leslie Dan Faculty of Pharmacy\, University of Toronto \nDaniel Wang is a Connaught scholar and PhD student in the lab of Shana Kelley\, University of Toronto. His research focuses on the enabling technology for next-generation cell therapy\, including cell sorting and bioprinting. As the co-author \, he published > 30 papers that have been cited over 2\,000 times.  \n\n\n\nCompany Spotlights\nAndras Nagy - panCELLaShreya Shukla - Notch TherapeuticsAndras Nagy - panCELLa \nFounder and Director\, panCELLa\nNagy is currently a Shawn Kimel Senior Scientist at the Lunenfeld-Tanenbaum Research Institute\, Sinai Health System\, Professor in the Department of Obstetrics & Gynaecology and Institute of Medical Science at the University of Toronto and Professor at the Australian Regenerative Medicine Institute in Monash University\, Melbourne. He holds a Tier I Canada Research Chair in Stem Cells and Regeneration. He is a Fellow of the Royal Society of Canada in the Life Sciences Division of the Academy of Science\, a Foreign Member of the Hungarian Academy of Science\, an Honorary Professor at the Helsinki University\, and a Distinguished Professor at the Honk Kong University. \nDr. Nagy’s endeavours have led to unprecedented breakthroughs in developmental genetics\, mouse and human pluripotent stem cell biology (both embryonic and reprogramming-induced)\, disease modelling and cell therapy approach. His team created the first Canadian human embryonic stem cell lines in early 2000. A decade later\, they developed the first method allowing the generation of iPS cell lines without any genetic change. Their approach allowed studying the reprogramming process at multiple OMICS levels\, virtually at a daily resolution from differentiated cells to pluripotency. His current research has become increasingly translational by addressing and developing solutions for the two most significant hurdles of cell therapies: safety and allogeneic cell acceptance without the need for suppression of the recipient’s immune system. His research has been aiming to advance medicine with a focus on currently incurable degenerative diseases\, such as blindness\, diabetes\, arthritis\, spinal cord injury\, multiple sclerosis\, haemophilia\, hypoparathyroidism and others. \nShreya Shukla - Notch Therapeutics \nCo-Founder and Director\, Research\, Notch Therapeutics  \nShreya Shukla is a Co-Founder and Director of Research at Notch Therapeutics. She oversees iPSC differentiation platform development and leads the design and optimization of the T cell differentiation process. She supports senior leadership for the ideation\, technical diligence and implementation of new programs and technologies in the Notch pipeline. She also contributes to relevant intellectual property strategy and patent filings related to novel product or process developments. Previously\, Shreya worked at CCRM as a scientist/entrepreneur\, where she drove forward the creation and launch of Notch Therapeutics as a new cell therapy company incubation within CCRM. As a co-inventor\, she designed and performed proof-of-concept studies to demonstrate therapeutic utility of intellectual property from her Ph.D that was subsequently in-licensed to Notch. Shreya has a B.S. in Biomedical Engineering from Georgia Institute of Technology in U.S.A. and completed her Ph.D. in Biomedical Engineering from Dr. Peter Zandstra’s stem cell bioengineering laboratory at the University of Toronto in Canada. \n\n\nDay 2 – Enabling Technologies\nWednesday\, July 21\, 1 p.m. to 3 p.m. – Next Session\nView Day 2 Agenda \nModerator: Shana Kelley\, Director\, Precision Medicine initiative (PRiME)\, University of Toronto \nOpening Remarks – 1:00pm: Shana Kelley\, Director\, Precision Medicine initiative (PRiME)\, University of Toronto \nGroup 1 Presenters – 1:05pm-1:45pm\nMaude Dumont-Lagacé – Associate Director of R&D and Special Projects\, ExCellThera\nPenney Gilbert – Associate Professor\, Institute of Biomedical Engineering\, University of Toronto\nRony Chidiac – Postdoctoral Fellow\, Stéphane Angers Lab\, Leslie Dan Faculty of Pharmacy\, University of Toronto \nPanel Discussion with Group 1 – 1:45pm-1:55pm: Moderated by Shana Kelley \nGroup 2 Presenters – 2:00pm-2:40pm\nSam Wadsworth – Chief Scientific Officer\, Aspect Biosystems\nLiliana Attisano – Professor\, Donnelly Centre for Cellular and Biomolecular Research\, University of Toronto\nMarie Abou Chakra – Research Associate\, Gary Bader Lab\, Donnelly Centre for Cellular and Biomolecular Research\, University of Toronto \nPanel Discussion with Group 2 – 2:40pm-2:50pm: Moderated by Shana Kelley \nClosing Remarks – 2:50pm \n\nAcademic Researchers\nLiliana\nAttisano Penney\nGilbertMaria\nAbou Chakra Rony\nChidiac Liliana\nAttisano  \nProfessor\, Donnelly Centre for Cellular and Biomolecular Research\, University of Toronto \nLiliana Attisano is a Professor and Interim Chair in the Dept. of Biochemistry\, with a laboratory based in the Donnelly Centre. Dr. Attisano’s lab is focused on studying the molecular events that underlie signalling cascades and elucidating how cells interpret contextual cues to control complex biological responses. Her lab uses cells\, mice and most recently human stem cell-derived organoid models to better understand how disruptions in signalling pathways underlie human disease processes including cancer and neurological disorders. \n  \nPenney\nGilbert \nAssociate Professor\, Institute of Biomedical Engineering\, University of Toronto \nPenney M. Gilbert is an Associate Professor at the University of Toronto in the Institute of Biomedical Engineering. Gilbert received her PhD from the University of Pennsylvania (2006) and conducted Postdoctoral studies at Stanford University (2007 – 2012). Her team engineers and studies three-dimensional models of human skeletal muscle and explores muscle stem cell mechanobiology with the goal of identifying signaling pathways that can be tweaked to boost the function of skeletal muscle stem cells in the body. She is recipient of an Ontario Early Researcher Award and holds a Canada Research Chair in Endogenous Repair.   \nMaria\nAbou Chakra  \nResearch Associate\, Gary Bader Lab\, Donnelly Centre for Cellular and Biomolecular Research\, University of Toronto \nMaria Abou Chakra is a trained biologist with a PhD in Computational & Mathematical Biology from McMaster University. During her graduate degree she trained in theoretical morphology in the lab of Jon Stone. She developed a mathematical model that explores both growth and form of sea urchin skeletons. After graduating she moved to Germany to work as a post-doctoral fellow at the Max Planck Institute for Evolutionary Biology. In the evolutionary theory department she was trained by Arne Traulsen in evolutionary game theory.  She developed models that capture and predict behaviors in complex social dilemmas such as Climate Change negotiations and Host parasite interactions. Currently since 2016 she has been working as research associate in the lab of Gary Bader developing 3D mathematical models that explore cell development. She is trying  to understand how cells control gene expression timing and cell fate decisions during development.  \nRony\nChidiac  \nPostdoctoral Fellow\, Stéphane Angers Lab\, Leslie Dan Faculty of Pharmacy\, University of Toronto \nI am a postdoctoral fellow in the laboratory of Dr. Stephane Angers at the Leslie Dan Faculty of Pharmacy at the University of Toronto. I hold a PhD in pathology and cell biology from the Université de Montréal. During my PhD\, I used proteomic approaches to elucidate signalling pathways activated by growth factors in endothelial cells during angiogenesis. My current research interest is to modulate Wnt pathway activity using novel antibody-based agonists selectively targeting Frizzled receptors recently developed by the Angers and Sidhu teams for regenerative medicine therapies. My main focus is to examine the therapeutic potential of our synthetic antibodies in normalizing pathological and leaky blood vessels in eye diseases. Also\, I am interested in activating Wnt pathway using selective antibodies to precisely control directed differentiation of hPSCs and cell fate specification for regenerative medicine applications. I am a member of the MbD cycle 2 teams. I was a 2019 PRiME fellowship awardee and I was recently awarded a postdoctoral fellowship award from the BrightFocus Foundation.   \n\nCompany Spotlights\nMaude Dumont-Lagacé - ExCellTheraSam Wadsworth - Aspect BiosystemsMaude Dumont-Lagacé - ExCellThera \nAssociate Director of R&D and Special Projects\, ExCellThera \nMaude Dumont-Lagacé completed a PhD in molecular biology with a specialization in immunobiology at the Université de Montréal\, Canada. She joined ExCellThera in 2018\, where she participates in clinical research focusing on UM171 expanded CB grafts. Working in close collaboration with the hematologists team leading the clinical trials at Maisonneuve-Rosemont Hospital\, she led the study of immune reconstitution in patients transplanted with UM171 expanded cord blood grafts. More recently\, she is exploring how cord blood expansion increases donor availability for different populations.  \n  \nSam Wadsworth - Aspect Biosystems \n \nChief Scientific Officer\, Aspect Biosystems \nSam Wadsworth\, Ph.D.\, Chief Scientific Officer & Co-Founder Aspect Biosystems. Sam has spent two decades driving developments in human tissue engineering. In 2013\, Sam co-founded the UBC spin-out\, Aspect Biosystems with Konrad Walus\, Simon Beyer and Tamer Mohamed. Aspect Biosystems is a biotechnology company creating bioprinted therapeutics as medicines of the future. Aspect is applying its microfluidic 3D bioprinting technology internally to develop these advanced cell therapies and partnering with leading researchers and industry innovators worldwide to tackle the biggest challenges in regenerative medicine. Sam will be discussing Aspect’s proprietary bioprinting technology and will describe how it has the potential to revolutionize the field of regenerative medicine by enabling a new generation of allogeneic cell therapies.
URL:https://mbd.ccrm.ca/event/cell-and-gene-therapies-innovations-showcase/
LOCATION:Virtual
CATEGORIES:Co-hosted Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210622T120000
DTEND;TZID=America/Toronto:20210622T130000
DTSTAMP:20260405T185234
CREATED:20210527T191759Z
LAST-MODIFIED:20210601T190458Z
UID:13747-1624363200-1624366800@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Juan Melero-Martin\, PhD - Harvard Medical School
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Juan Melero-Martin\, PhD\, Associate Professor of Surgery\, Boston Children’s Hospital\, Harvard Medical School. \nThe title of this talk will be\, “Bioengineering drug-secreting vascular networks from pluripotent stem cells” \n Register for this virtual event. \n \nMore About Juan Melero-Martin:\nProfessor Melero-Martin graduated in Chemical Engineering from the University of Seville\, Spain\, in 1998. After working three years in industry\, he went on to earn a PhD in Biochemical Engineering from the University of Birmingham\, UK\, in 2005. He then trained as a post-doctoral fellow in the Vascular Biology Program at Boston Children’s Hospital. He joined the Department of Cardiac Surgery at Boston Children’s Hospital in 2008. Currently\, he is an Associate Professor of Surgery\, Harvard Medical School\, and the inaugural incumbent of an endowed Chair in Cardiac Surgery at Boston Children’s Hospital. \nProfessor Melero-Martin’s research is focused on how to build vascular networks and vascularize tissues. His laboratory is a reference in human blood-derived circulating endothelial colony-forming cells (ECFCs) and has contributed multiple original papers on various aspects of ECFC biology. His group has developed novel approaches to bioengineer vascular networks and has shown that bioengineered vascular networks can be generally used to harness the regenerative potential of other stem cells. In addition\, his group developed a model that uses genetically engineered blood vessels to achieve the controlled release of therapeutic proteins in vivo. \n Learn more about Juan Melero-Martin’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-juan-melero-martin-phd-harvard-medical-school/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210519T150000
DTEND;TZID=America/Toronto:20210519T170000
DTSTAMP:20260405T185234
CREATED:20210323T202553Z
LAST-MODIFIED:20210505T192900Z
UID:13286-1621436400-1621443600@mbd.ccrm.ca
SUMMARY:Pitch Competition: Building a Biotech Venture program
DESCRIPTION:Learn how the next generation of regenerative medicine researchers at the University of Toronto and its affiliated hospitals are preparing to translate their discoveries toward impact. At the Building a Biotech Venture Pitch Competition\, six trainee-led teams will pitch their regenerative medicine-related products or ventures to an expert panel of judges and compete for up to $25\,000 in research funding. \nRegister now to watch the teams compete \nThe competition is the culmination of Medicine by Design’s Building a Biotech Venture program\, offered in partnership with H2i. Over the past three months\, the program has offered workshops and mentoring to help teams advance company or product concepts based on their regenerative medicine research. The teams with the highest potential for company creation have been selected to take part in the pitch competition.  \n\nMeet the judges\nMike CookeAvi GoldfarbRobin QuirkAndrea SampsonEmily TitusMike Cooke \nMike Cooke\, PhD\, is the Co-Founder & CEO of AmacaThera. AmacaThera is a Toronto-based biotechnology company focused on developing and commercializing a unique\, injectable hydrogel platform technology for a wide range of medical applications. Mike co-founded the company along with renowned biomaterials scientist\, Molly Shoichet. Mike co-developed the first product for AmacaThera\, a sustained analgesic for post-operative pain\, which he pitched to both UTEST and OBIO and secured dilutive and non-dilutive seed investment. Mike has secured over C$12MM in venture capital financing for AmacaThera. Mike completed his PhD at Durham University (UK) and a post-doctoral fellowship in the Shoichet Lab at the University of Toronto. Mike is currently pursuing a Global Professional Master of Laws (GPLLM) in Business Law at the University of Toronto. \nAvi Goldfarb \nAvi Goldfarb\, PhD\, is the Rotman Chair in Artificial Intelligence and Healthcare\, and Professor of Marketing\, at the Rotman School of Management\, University of Toronto. Avi is also Chief Data Scientist at the Creative Destruction Lab where he manages the health stream\, Senior Editor at Marketing Science\, and a Research Associate at the National Bureau of Economic Research. He has published over 80 academic articles in a variety of outlets in marketing\, statistics\, law\, management\, refugee studies\, medicine\, computing\, and economics. Along with Ajay Agrawal and Joshua Gans\, Avi is the author of the book Prediction Machines: The Simple Economics of Artificial Intelligence and editor of the NBER book The Economics of Artificial Intelligence: An Agenda. Avi received his PhD in economics from Northwestern University. Robin Quirk \nRobin Quirk\, PhD\, MBA is the Director of Technology Sourcing and Venture Development at CCRM. Robin has over 20 years of experience working with regenerative medicine start-up companies. He started his career as an industry-trained pharmacist before moving into tissue engineering research. Robin joined CCRM to support the commercial development of early-stage ideas. He leads the team responsible for identifying and developing promising technologies and nurturing them to the company creation stage by strategically leveraging CCRM’s expertise and infrastructure. \nAndrea Sampson \nAndrea Sampson is Co-Founder & Executive Speaker Coach at Talk Boutique. She is a former Strategist and Consultant and has spent over 25 years working in marketing and advertising\, presenting and developing strategies for Fortune 100 companies. With a natural talent for developing compelling stories and persuasive content\, Andrea is sought after in assisting teams and executives develop their presentations or pitches. Four years ago\, Andrea’s passion for ideas led her to TEDxToronto where she volunteered initially as a Speaker Coach\, then as the Director of Programming in 2015 and the Conference Co-Chair in 2016. This voluntary role was instrumental in the creation of Talk Boutique\, a speaker management\, development and representation company. Andrea was the Co-Director of the 2017 Singularity University Canada Summit.Emily Titus \nEmily Titus\, PhD\, is Vice President\, Process Sciences at Notch Therapeutics. Previously\, she was Vice President\, Technology Advancement at CCRM\, where she built cell reprogramming\, genome engineering\, and pluripotent stem cell differentiation programs and led the formation of Notch Therapeutics as part of CCRM’s company incubation program. Emily earned a PhD from the Institute of Biomedical Engineering at the University of Toronto\, where she used a combination of laboratory and bioinformatics approaches to define and interpret gene regulatory networks controlling embryonic stem cell fate decisions. \n\n\nMeet the teams\nDandelion Biologics\nDandelion Biologics provides an advanced antibody development platform for challenging therapeutic targets. \nHDAX Therapeutics\nHDAX Therapeutics focuses on developing epigenetic-targeting treatments through designing and synthesizing the next generation of life-improving medicines to tackle unmet healthcare needs in cancer and central nervous system disorders.\n \nLaetech\nLaetech harnesses the regenerative capacity of fat to improve the clinical outcomes of cosmetic and reconstructive surgical procedures.\n \nLifeScreen\nLifeScreen is developing a new approach to personal wellness using biological age. \n\nMyoThera\nMyoThera identifies therapeutic targets to boost the impaired regenerative capacity of skeletal muscle in Duchenne muscular dystrophy patients. \n\nPancraTECH\nPancraTECH is using stem cells to generate a cellular therapy for patients with type 1 diabetes.
URL:https://mbd.ccrm.ca/event/pitch-competition-building-a-biotech-venture-program/
CATEGORIES:Co-hosted Events
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210518T120000
DTEND;TZID=America/Toronto:20210518T130000
DTSTAMP:20260405T185234
CREATED:20210316T173415Z
LAST-MODIFIED:20210728T154522Z
UID:13217-1621339200-1621342800@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Jeffrey Millman\, PhD - Washington University in St. Louis
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Jeffrey Millman\, PhD\, Assistant Professor of Medicine and Biomedical Engineering\, Washington University in St. Louis. \nThe title of this talk will be\, “Engineering Human Islets From Stem Cells For Diabetes Cellular Therapy” \n Register for this virtual event. \n \nMore About Jeffrey Millman:\nProfessor Jeffrey Millman received his bachelor’s degree from North Carolina State University and PhD in Chemical Engineering from MIT. He completed his post-doctoral training in the laboratory of Dr. Douglas Melton at Harvard University. He was recruited by the Division of Endocrinology\, Metabolism and Lipid Research in the Department of Medicine at the Washington University School of Medicine as an Assistant Professor in 2015 and is an affiliated faculty in the Department of Biomedical Engineering. \nHis current research is focused on synergizing both biomedical engineering and cell biology approaches to use stem cells for the study and treatment of diabetes. He is developing new approaches for the differentiation of insulin-producing islets from stem cells and improving their utility for cell replacement therapy and in vitro disease models. His innovations have been licensed to several biotechnology and startup companies in the diabetes space. His laboratory is supported by the NIH NIDDK and JDRF. \nProfessor Millman received an American Institute of Chemical Engineering 35 Under 35 Award in 2017\, Chemical and Biomolecular Engineering Distinguish Young Alumni Award from North Carolina State University in 2019\, and was named a Cellular and Molecular Bioengineering (CMBE) Rising Star by Biomedical Engineering Society in 2021. \n Learn more about Jeffrey Millman’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-jeffrey-millman-phd-washington-university-in-st-louis/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210507T100000
DTEND;TZID=America/Toronto:20210507T110000
DTSTAMP:20260405T185234
CREATED:20210419T161645Z
LAST-MODIFIED:20210507T143446Z
UID:13651-1620381600-1620385200@mbd.ccrm.ca
SUMMARY:Grand Questions: Glimpse the future of regenerative medicine
DESCRIPTION:Please use event link: https://www.youtube.com/watch?v=gzZw6yeGYLU. \nLast year\, Medicine by Design challenged its researchers to think boldly about how they would solve regenerative medicine’s grand questions such as how to create tissues that outperform nature to resist novel infections or cancer or how to make regenerative medicine affordable and accessible to everyone. Now\, we are investing $3 million in some of their most ambitious ideas with the ultimate goal of preparing the foundation for the future of human health. \nRegister now\nAt the event\n\n10 a.m. – Greetings from Christine Allen\nAssociate Vice-President and Vice-Provost\, Strategic Initiatives\, University of Toronto and Professor\, Leslie Dan Faculty of Pharmacy\n10:05 a.m. – Announcement of Grand Questions funded projects\nMeet the extraordinary Grand Questions teams that will help make regenerative medicine solutions a reality for all disease.\n10:10 a.m. – Panel discussion\n“Ambitious and provocative – expanding the frontiers of regenerative medicine”\nModerated by Janet Rossant\, President and Scientific Director\, The Gairdner Foundation and Chief of Research Emeritus\, SickKids Research Institute.\nThis interactive panel discussion will focus on why ambitious\, provocative and non-obvious solutions are the future of regenerative medicine.
URL:https://mbd.ccrm.ca/event/grand-questions-glimpse-the-future-of-regenerative-medicine/
CATEGORIES:Other Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210506T140000
DTEND;TZID=America/Toronto:20210506T153000
DTSTAMP:20260405T185234
CREATED:20210422T022852Z
LAST-MODIFIED:20210505T042142Z
UID:13705-1620309600-1620315000@mbd.ccrm.ca
SUMMARY:Cycle 2 Discussion Group: How are stemness properties of blood relevant for cell replacement therapies?
DESCRIPTION:Medicine by Design is launching a new discussion group series to provide an opportunity for investigators and trainees from Cycle 2 projects to connect with each other\, discuss overlapping interests\, and share information about the development and implementation of new technologies and tools that could be applicable to multiple projects. Each session will feature two speakers from Cycle 2 projects\, followed by a group discussion. \nSession Title: How are stemness properties of blood relevant for cell replacement therapies? \nRegister now\n\nMeeting Chair and Speaker\n\nDr. John Dick\nSenior Scientist\, Princess Margaret Cancer Centre\, University Health Network \n \nPresentation Title: Age related clonal hematopoiesis drives immune function and inflammatory processes \nCycle 2 Project Lead:\n“Investigating how age-related clonal hematopoiesis drives HSC stemness properties and how this leads to inflammatory diseases of the heart” \nSpeaker\nDr. Mathieu Lupien\nSenior Scientist\, Princess Margaret Cancer Centre\, University Health Network \n \nPresentation Title: Cellular heterogeneity from chromatin variants at single cell resolution \nCycle 2 Project:\n“Investigating how age-related clonal hematopoiesis drives HSC stemness properties and how this leads to inflammatory diseases of the heart” \n\nAbout Cycle 2 Thematic Discussion Groups\nThemes will focus on a technology or platform that is applicable across multiple Cycle 2 projects (e.g. single-cell sequencing\, imaging\, synthetic biology) or cross-cutting scientific themes (e.g. inflammation). The discussion groups will be held bi-monthly. \nEach meeting will be chaired by one of our Cycle 2 principal investigators. If you or an investigator on your team are interested in chairing an upcoming session\, or have a topic you would like to see discussed\, please reach out to Stephanie Hume (stephanie.hume@utoronto.ca).
URL:https://mbd.ccrm.ca/event/cycle-2-discussion-group-how-are-stemness-properties-of-blood-relevant-for-cell-replacement-therapies/
CATEGORIES:Discussion Groups
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210428T100000
DTEND;TZID=America/Toronto:20210428T110000
DTSTAMP:20260405T185234
CREATED:20210401T161249Z
LAST-MODIFIED:20210407T012959Z
UID:13394-1619604000-1619607600@mbd.ccrm.ca
SUMMARY:Conversations in Convergence: Stephanie Protze\, PhD\, and Eric Strohm\, PhD
DESCRIPTION:Join us for our Conversations in Convergence series which is an interactive discussions between Medicine by Design researchers who study similar questions using different approaches. \nThe goal is to foster cross-disciplinary discussions in support of convergence\, which is the integration of approaches from engineering\, science\, medicine and other fields to expand knowledge and spark innovation. The researchers will discuss how their unique perspectives\, knowledge and ideas inform their work\, and how their diverse approaches intersect and complement one another to advance regenerative medicine. \nOur speakers will be: \n\nStephanie Protze\, PhD – Principal Investigator\, McEwen Stem Cell Institute\, at the University Health Network and Assistant Professor\, Department of Molecular Genetics\, University of Toronto\nEric Strohm\, PhD – Post-Doctoral Fellow\, Craig Simmons Cellular Mechanobiology Lab\, Department of Mechanical and Industrial Engineering\, University of Toronto\n\nRegister Now\n \nDr. Protze studies how the human heart develops with a specific focus the cardiac conduction system that regulates the heartbeat. Her lab uses pluripotent stem cells\, single cell transcriptomics\, and electrophysiology assays to study heart development and diseases in a petri-dish. In addition\, her team explores the application of the stem cell-derived conduction system cells in cell therapy approaches to treat heart rhythm disorders. \n  \nDr. Strohm post-doctoral fellow work uses microscale ultrasound to measure the contractile forces of cardiomyocyte cells and tissues. Using a custom-built system\, the contractions are rapidly measured using ultrasound with sub-micrometer precision to determine the forces exerted. The system is highly versatile and can measure cell contractility in a range of platforms\, including standard cell culture plates and specialized heart-on-a-chip systems. Applications include evaluating drug cardiotoxicity\, screening drug candidates to treat heart failure\, and quantifying stem cell-based therapies for regenerative cardiac repair.
URL:https://mbd.ccrm.ca/event/conversations-in-convergence-stephanie-protze-phd-and-eric-strohm-phd/
CATEGORIES:Other Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210426T160000
DTEND;TZID=America/Toronto:20210426T170000
DTSTAMP:20260405T185234
CREATED:20210409T162324Z
LAST-MODIFIED:20210412T154534Z
UID:13510-1619452800-1619456400@mbd.ccrm.ca
SUMMARY:Careers by Design: Building a Professional Development Blueprint
DESCRIPTION:Register now for new sessions of Careers by Design: Building a Professional Development Blueprint\, hosted by Medicine by Design’s Healthy and Inclusive Labs Committee. The series continues on Monday\, April 26 from 4 p.m. to 5 p.m. with a discussion on Individual Development Plan (IDP). \nThis five-part workshop series aims to foster healthy lab environments that support the inclusion and well-being of all members\, while empowering graduate students\, post-doctoral fellows and research/scientific associates to realize their academic and professional goals. All workshops will be led by Nana Lee\, PhD\, Director\, Graduate Professional Development & Mentorship\, and Assistant Professor in the departments of Biochemistry & Immunology at the University of Toronto (U of T). \nMonday\, April 26 – Workshop #2 : Creating Your Individual Development Plan \nTrainees will begin the process of creating their Individual Development Plan and will receive feedback on best avenues to attain their SMART goals and an overview of diverse career options. The workshop will build on our first session in March\, which introduced the Individual Development Plan\, a tool developed by the Healthy and Inclusive Labs Committee to support trainee well-being and success. \nIf you missed the first session\, you can still participate in the workshop series. The recording from Workshop 1 will be available on our website and shared via email next week. \nRegister for this virtual event\n*Once registered\, you will be automatically enrolled in the remaining workshops.  \nThis series is for trainees in past and/or current Medicine by Design-funded labs. To gain the full benefit of the program\, it is recommended that participants attend all sessions. \nIf you have any immediate questions regarding this program\, please contact us at info.mbd@utoronto.ca. \n\nWorkshop schedule:\n*All workshops will take place from 4 p.m. to 5 p.m.\n\n\nWorkshop 1: Monday\, March 29 – Recording will be available next week.\nIndividual Development Plans Intro – Optimizing Research Productivity and Professional Development \nAt the end of this workshop\, both faculty and mentees (students and postdocs) will have an understanding of how to effectively use the AAAS individual development plan to plan SMART (Specific\, Measurable\, Attainable\, Relevant\, Time-bound) goals in research productivity and career development while using the tool for optimal mentorship. \n\n\nWorkshop 2: Monday\, April 26 – NEXT Session\nCreating Your Individual Development Plans \nLearners will be given peer and instructor-led feedback on best avenues to attain their SMART goals and an overview of the multiple career options available for them. \n\n\nWorkshop 3: Monday\, May 31\nMeaningful Engagement \nParticipants will gain an understanding of introductory design-thinking principles to brainstorm their wayfinding purpose compass around what they love\, are good at and care about. We will also discuss specific action items for learners to help make their dream purpose a reality. \n\n\nWorkshop 4: Monday\, June 28\nStorytelling \nAt the end of this workshop\, trainees will understand the difference between an academic and non-academic job application (CV vs resume)\, how to write the stellar cover letter\, and gain tips on interviewing and a LinkedIn presence. \n\n\nWorkshop 5: Monday\, July 26\nWellness and Equity Diversity and Inclusion in Professional and Career Development \nThe goal of this workshop is to introduce or re-emphasize the concepts of an equity-minded scholar\, allyship and wellness issues and how to bring these concepts into daily practice as a graduate student\, postdoctoral fellow or faculty member towards any career. \n\n\nWorkshop 6: Monday\, August 30\nImplementation/Feedback on Job Applications \nAt the end of this workshop\, trainees will receive peer feedback (guided by the instructor) on their job applications to any career of their choice and a big picture review of workshops I-IV to strategically move forward in their professional and career development.
URL:https://mbd.ccrm.ca/event/careers-by-design-building-a-professional-development-blueprint/
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210414T120000
DTEND;TZID=America/Toronto:20210414T130000
DTSTAMP:20260405T185234
CREATED:20210323T181821Z
LAST-MODIFIED:20210409T164438Z
UID:13297-1618401600-1618405200@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Sonja Schrepfer\, PhD\, University of California San Francisco (UCSF)
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Sonja Schrepfer\, PhD\, Professor\, University of California San Francisco (UCSF)\, and Scientific Founder and SVP\, Sana Biotechnology Inc. \nThe title of this talk will be\, “Identifying and overcoming the immunological hurdle in stem cell therapy for regenerative medicine” \n Register for this virtual event. \n \nMore About Sonja Schrepfer:\nDr. Schrepfer’s research career has been dedicated to making fundamental discovers in transplant and stem cell immunobiology. Work by Dr. Schrepfer is at the forefront of stem immunobiology and paves the way for treatment of a wide range of diseases – from supporting functional recovery of failing myocardium to the derivation of other cell types to treat diabetes\, blindness\, cancer\, lung\, neurodegenerative\, and related diseases. She spent many years examining in detail the fetomaternal interface for application to the envisioned cell therapy. Her work with one of the most antigenic phenotypes\, antigen-presenting endothelial cells\, demonstrates that hypo-immunogenic cells reliably evade immune rejection in allogeneic recipients that are entirely mismatched in their major histocompatibility complex profile\, and further\, these cells show long-term survival without immunosuppression in mice and humanized mice (published in Nature Biotechnology in 2019 and JEM in 2021). These findings – truly hypo-immunogeneic iPSCs – achieve the “holy grail” of stem cell immunobiology. \nDr. Schrepfer\, Professor at the University of California San Francisco (UCSF)\, and Scientific Founder and SVP from Sana Biotechnology Inc.\, was trained as cardiac surgeon in the Cardiothoracic Surgery Departments in Munich and Hamburg\, Germany before pursuing a career as a full-time scientist. She received her PhD in transplant immunology and joined Stanford University to start her own research group in 2007 in the Department of Cardiothoracic Surgery. Dr. Schrepfer’s findings have been highlighted in leading journals such as Nature and Science and she received numerous awards\, such as the prestigious DFG-Heisenberg professorship (2009)\, the Innovation Award from Academia (Germany; 2014)\, the science award from the German Academy of Sciences (Leopoldina; 2015)\, and the Galenus-von-Pergamon Medal in Basic Medical Sciences (2019). \n Learn more about Sonja Schrepfer’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-sonja-schrepfer-phd-professor-university-of-california-san-francisco-ucsf/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210329T160000
DTEND;TZID=America/Toronto:20210329T170000
DTSTAMP:20260405T185234
CREATED:20210310T214107Z
LAST-MODIFIED:20210322T201938Z
UID:12891-1617033600-1617037200@mbd.ccrm.ca
SUMMARY:Careers by Design: Building a Professional Development Blueprint
DESCRIPTION:  \nJoin us on March 29 for the launch of Careers by Design: Building a Professional Development Blueprint. Organized by Medicine by Design’s Healthy and Inclusive Labs Committee.  \nThis new workshop series aims to foster healthy lab environments that support the inclusion and well-being of all members\, while empowering graduate students\, post-doctoral fellows and research/scientific associates to realize their academic and professional goals. \nWorkshop #1: Optimizing Research Productivity and Professional Development  \nExplore and learn how to use the IDP at our first workshop on Monday\, March 29\, from 4 p.m. to 5 p.m. We encourage graduate students\, post-doctoral fellows\, research/scientific associates and principal investigators from past or current Medicine by Design-funded labs to join us for this first session.   \nRegister for this virtual event\n*Once registered please become familiar and/or fill out the Science Careers IDP to prepare for the first worskhop. A resource video can be found here on how to fill it out. \nThis series will support the introduction of the Individual Development Plan (IDP)\, created by the Healthy and Inclusive Labs Committee as a tool to support trainee well-being and success. Medicine by Design encourages all labs in our community to adopt this tool\, which facilitates open and ongoing conversations between trainees and supervisors about goals\, expectations and professional development. Learn more about the IDP.   \nAll workshops will be led by Nana Lee\, PhD\, Director\, Graduate Professional Development & Mentorship\, and Assistant Professor in the departments of Biochemistry & Immunology at the University of Toronto (U of T).  .   \nIf you have any immediate questions regarding this program\, please contact us at (info.mbd@utoronto.ca). \n\nWorkshop schedule:\n\n\nWorkshop 1: Monday\, March 29\nIndividual Development Plans Intro – Optimizing Research Productivity and Professional Development\nAt the end of this workshop\, both faculty and mentees (students and postdocs) will have an understanding of how to effectively use the AAAS individual development plan to plan SMART (Specific\, Measurable\, Attainable\, Relevant\, Time-bound) goals in research productivity and career development while using the tool for optimal mentorship. \nWorkshop 2: Monday\, April 26 \nDiscussion on Individual Development Plans\nLearners will be given peer and instructor-led feedback on best avenues to attain their SMART goals and an overview of the multiple career options available for them. \nWorkshop 3: Monday\, May 31\nMeaningful Engagement\nParticipants will gain an understanding of introductory design-thinking principles to brainstorm their wayfinding purpose compass around what they love\, are good at and care about. We will also discuss specific action items for learners to help make their dream purpose a reality. \nWorkshop 4: Monday\, June 28\nStorytelling\nAt the end of this workshop\, trainees will understand the difference between an academic and non-academic job application (CV vs resume)\, how to write the stellar cover letter\, and gain tips on interviewing and a LinkedIn presence.\n\nWorkshop 5: Monday\, July 26\nWellness and Equity Diversity and Inclusion in Professional and Career Development \nThe goal of this workshop is to introduce or re-emphasize the concepts of an equity-minded scholar\, allyship and wellness issues and how to bring these concepts into daily practice as a graduate student\, postdoctoral fellow or faculty member towards any career. \nWorkshop 6: Monday\, August 30\nImplementation/Feedback on Job Applications\nAt the end of this workshop\, trainees will receive peer feedback (guided by the instructor) on their job applications to any career of their choice and a big picture review of workshops I-IV to strategically move forward in their professional and career development.
URL:https://mbd.ccrm.ca/event/nana-lee-idp/
LOCATION:Virtual
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210316T120000
DTEND;TZID=America/Toronto:20210316T130000
DTSTAMP:20260405T185234
CREATED:20210211T171832Z
LAST-MODIFIED:20210216T201224Z
UID:12647-1615896000-1615899600@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Magdalena Götz\, PhD - University of Munich and Helmholtz Center Munich
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Magdalena Götz\, PhD\, professor at the Biomedical Center\, University of Munich and Institute for Stem Cell Research\, Helmholtz Center Munich\, Germany. \nThe title of this talk will be\, “Novel mechanisms of neurogenesis and neural repair” \n Register for this virtual event. \n \nMore About Magdalena Götz: \nProfessor Götz’s lab studies the mechanisms of neurogenesis in order to implement them for neuronal repair. She will present recent work on a novel centrosomal protein\, Akna\, regulated with great precision in subsets of neural stem cells. This led Professor Götz’s lab to unravel an unprecedented centrosome heterogeneity in human neural stem cells revealing and verifying novel disease candidates. She will proceed to present recent data on a master regulator of nuclear compartmentalization by liquid phase transition with key roles in promoting neural stem cell self-renewal and neurogenesis. Trnp1 is also critical for direct neuronal reprogramming which leads to discuss recent progress in direct neuronal reprogramming as a means to replace lost neurons after brain injury. The presentation will be concluded by discussing the integration of replaced neurons into the circuitry of the murine cerebral cortex and present unpublished data about the mechanisms regulating this integration. Taken together\, our knowledge about basic mechanisms of neurogenesis allowed making great strides towards neuronal repair. \n Learn more about Magdalena Götz’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-magdalena-gotz-phd-university-of-munich-and-helmholtz-center-munich/
LOCATION:Virtual
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210302T100000
DTEND;TZID=America/Toronto:20210302T120000
DTSTAMP:20260405T185234
CREATED:20210111T190722Z
LAST-MODIFIED:20210429T142434Z
UID:12004-1614679200-1614686400@mbd.ccrm.ca
SUMMARY:Building a Biotech Venture
DESCRIPTION:  \nNext session: March 2\, 10 a.m. to 12 p.m. – 10 Point Plan Workshop\n\nRegistration Now Closed – Email info.mbd@utoronto.ca if you have any questions. \nLooking to translate your regenerative medicine research or technology into a product or venture but don’t know where to start? \nTake your first steps toward entrepreneurship with Building a Biotech Venture\, a new program for regenerative medicine-focused trainees in labs at the University of Toronto or its affiliated hospitals\, offered in partnership with the Health Innovation Hub (H2i)\, a campus-linked accelerator at the Temerty Faculty of Medicine at U of T. \nThrough a series of workshops over winter/spring 2021\, you will: \n\nlearn how to think about your research in terms of a product or business;\nconnect with peers to form a venture team;\ndevelop your product or venture “story”;\nbuild a business canvas and pitch deck; and\nreceive mentoring and guidance from industry experts throughout the process.\n\nThe program will culminate in a pitch competition in spring 2021 where the winning team will receive up to $25\,000 in research funding to advance their product or venture concept. \nThis is a virtual event \n\nBuilding a Biotech Venture program breakdown:\n\n\nSession 1: Information Session – **Note: Live session has passed but you can still participate in the program provided you have registered by Feb. 23. \nWatch recording here\, or you can review the FAQ.\nJan. 26\, 11 a.m. to 12 p.m.\nThis session will provide an overview of the program and how to enroll\, as well as an introduction to H2i’s 10-point plan\, which outlines 10 key elements of a business canvas. Medicine by Design will help facilitate venture team creation between session 1 and session 2 for those who do not have an existing team.\nSession 2: H2i’s 10-Point Plan Workshop\nRegistration Now Closed – Email info.mbd@utoronto.ca if you have any questions.\nMarch 2\, 10 a.m. to 12 p.m.\nTeams will dive into more detail on H2i’s 10-point plan\, and start developing a venture one-pager and a pitch deck on their venture concept. Mentors from H2i’s community will work with teams during the workshop to provide feedback. Post-workshop\, teams will be assigned H2i mentors and receive ongoing mentoring to further develop their business cases and pitch decks.\nSession 3: Medicine by Design Pitch Competition\nSpring 2021\nTeams who attended the session 2 workshop are invited to apply to this pitch competition. The winning team will receive up to $25\,000 in research funding to advance their product concept.\n\nIf you have any immediate questions regarding this program\, please contact Stephanie Hume (stephanie.hume@utoronto.ca).
URL:https://mbd.ccrm.ca/event/building-a-biotech-venture/
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210216T120000
DTEND;TZID=America/Toronto:20210216T130000
DTSTAMP:20260405T185234
CREATED:20201222T071349Z
LAST-MODIFIED:20210202T165247Z
UID:11577-1613476800-1613480400@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Manu Platt\, PhD - Georgia Institute of Technology\, and Emory University
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Manu Platt\, PhD\, associate professor at the Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology\, and Emory University. \nThe title of this talk will be\, “Things Fall Apart: Proteolytic Networks in Tissue Destructive Diseases” \n Register for this virtual event \n \nMore About Manu Platt:\nManu Platt received his BS in biology from Morehouse College in 2001 and his PhD from the Georgia Tech and Emory joint program in biomedical engineering in 2006. He finished his post–doctoral training at MIT in orthopedic tissue engineering and systems biology prior to returning to Georgia Tech and Emory’s Joint Department of Biomedical Engineering in 2009\, where he has since been promoted and tenured. His research centres on proteolytic mechanisms of tissue remodeling during disease progression using both experimental and computational approaches. \nIntegrated with his research program is his mentoring goal of changing the look of the next generation of scientists and engineers to include all colours\, genders\, and backgrounds. Aligned with that goal\, Dr. Platt\, along with Bob Nerem\, co-founded and co-directs Project ENGAGES (Engaging the Next Generation At Georgia Tech in Engineering and Science)\, a program paying African-American high school students from Atlanta Public Schools to be researchers in Georgia Tech labs since 2013.
URL:https://mbd.ccrm.ca/event/global-speaker-series-manu-platt-phd-georgia-institute-of-technology-and-emory-university/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210210T110000
DTEND;TZID=America/Toronto:20210210T120000
DTSTAMP:20260405T185234
CREATED:20210201T142350Z
LAST-MODIFIED:20210429T141611Z
UID:12330-1612954800-1612958400@mbd.ccrm.ca
SUMMARY:Conversations in Convergence: Yun Li\, PhD\, and Erica Scott\, PhD
DESCRIPTION:Join us for our first edition of Conversations in Convergence\, a series of interactive discussions between Medicine by Design researchers who study similar questions using different approaches. \nOur first speakers will be: \n\nYun Li\, PhD – Scientist\, Developmental & Stem Cell Biology\, The Hospital for Sick Children; Assistant Professor\, Department of Molecular Genetics\, University of Toronto; and Medicine by Design Investigator \nErica Scott\, PhD – Post-Doctoral Fellow\, Wheeler Microfluidics Lab\, Department of Chemistry and Institute of Biomaterials & Biomedical Engineering\, University of Toronto; and 2018 Medicine by Design Post-Doctoral Fellowship award winner  \n\n \nDr. Li studies how the human brain is formed\, what makes the human brain different from that of the other species\, and how disorders such as autism impact its normal development and function. She uses pluripotent stem cell\, genome editing\, and 3-dimensional organoid technologies to study brain development in a dish.  \nIn Dr. Scott’s post-doctoral fellowship\, she is developing a tool to analyze neural stem cell networks at single-cell resolution. This tool combines a single cell laser lysis technique\, microfluidics and RNA and DNA sequencing. Dr. Scott aims to describe the high degree of variability between neural stem cells and their environment to best harness their therapeutic potential.  \n\nThe goal of Conversations in Convergence is to foster cross-disciplinary discussions in support of convergence\, which is the integration of approaches from engineering\, science\, medicine and other fields to expand knowledge and spark innovation. The researchers will discuss how their unique perspectives\, knowledge and ideas inform their work\, and how their diverse approaches intersect and complement one another to advance regenerative medicine.  \nRegister now\n 
URL:https://mbd.ccrm.ca/event/conversations-in-convergence-february-2020/
CATEGORIES:Other Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210203T150000
DTEND;TZID=America/Toronto:20210203T163000
DTSTAMP:20260405T185234
CREATED:20210120T214054Z
LAST-MODIFIED:20210121T000410Z
UID:12153-1612364400-1612369800@mbd.ccrm.ca
SUMMARY:Cycle 2 Discussion Group: Applying single-cell RNA sequencing technologies to your research
DESCRIPTION:Medicine by Design is launching a new discussion group series to provide an opportunity for investigators and trainees from Cycle 2 projects to connect with each other\, discuss overlapping interests\, and share information about the development and implementation of new technologies and tools that could be applicable to multiple projects. Each session will feature two speakers from Cycle 2 projects\, followed by a group discussion. \n  \nRegister now\n  \n\nChair\n\nDr. Michael Laflamme\nSenior Scientist\, McEwen Stem Cell Institute\, and Staff Pathologist\,\nUniversity Health Network\n \n \nCycle 2 Project Lead:\n“Cardiac regeneration using pluripotent stem cells” \nSpeakers\nDr. Slava Epelman\nScientist\, Toronto General Hospital Research Institute and Staff Cardiologist\,\nPeter Munk Cardiac Centre\, UHN \n \nCycle 2 projects:\n“Cardiac regeneration using pluripotent stem cells” (Lead PI: Michael Laflamme)\n“Investigating how age-related clonal hematopoiesis drives HSC stemness properties and how this leads to inflammatory diseases of the heart” (Lead PI: John Dick) \nProfessor Gary Bader\nDonnelly Centre for Cellular and Biomolecular Research and the\nDepartment of Molecular Genetics\, University of Toronto\n \n \nCycle 2 Projects:\n“Stem cell- based approaches to endogenous repair of the brain and skeletal muscle” (Lead PI: Freda Miller)\n“Development of novel cell and tissue therapies to treat liver failure” (Lead PI: Gordon Keller) \n“Investigating how age-related clonal hematopoiesis drives HSC stemness properties and how this leads to inflammatory diseases of the heart” (Lead PI: John Dick) \n\nAbout Cycle 2 Thematic Discussion Groups\nThemes will focus on a technology or platform that is applicable across multiple Cycle 2 projects (e.g. single-cell sequencing\, imaging\, synthetic biology) or cross-cutting scientific themes (e.g. inflammation). The discussion groups will be held bi-monthly. \nEach meeting will be chaired by one of our Cycle 2 principal investigators. If you or an investigator on your team are interested in chairing an upcoming session\, or have a topic you would like to see discussed\, please reach out to Stephanie Hume (stephanie.hume@utoronto.ca).
URL:https://mbd.ccrm.ca/event/cycle-2-thematic-discussion-group-applying-single-cell-rna-sequencing-technologies-to-your-research/
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20210119T120000
DTEND;TZID=America/Toronto:20210119T130000
DTSTAMP:20260405T185234
CREATED:20201221T222251Z
LAST-MODIFIED:20210113T203542Z
UID:11573-1611057600-1611061200@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Allon Klein\, PhD - Harvard University
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Allon Klein\, PhD\, an Associate Professor of Systems Biology at Harvard Medical School. \nThe title of this talk will be\, “Lineage tracing on transcriptional landscapes” \n Register for this virtual event. \n  \n \nMore About Allon Klein: \nProfessor Klein is an Associate Professor of Systems Biology at Harvard Medical School. He obtained his PhD in physics with Prof. Ben Simons (Cambridge University)\, and a postdoc in experimental systems biology with Prof. Marc Kirschner (Harvard Medical School). Dr. Klein studies how cells make fate choices in developing and adult tissues. He pioneered droplet microfluidics for single-cell RNA-Seq\, computational methods for analyzing single-cell genomics data\, and methods for quantitative clonal analysis. He focuses on the early embryo\, epithelial tissues and the hematopoietic system as model systems. His work includes the discovery of a cell type in the airway epithelium (the pulmonary ionocyte)\, defining the identity of red blood cell progenitors\, and establishing the transcriptional dynamics of early vertebrate development at single cell resolution. In 2018\, Dr. Klein’s work mapping embryonic development in vertebrates was recognized by the AAAS “Breakthrough of the Year\,” and in 2020 he received the Dr. Susan Lim Award for Outstanding Young Investigator from the International Society for Stem Cell Research (ISSCR). \n Learn more about Allon Klein’s lab
URL:https://mbd.ccrm.ca/event/global-speaker-series-allon-klein-phd-harvard-medical-school/
LOCATION:Virtual
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20201215T120000
DTEND;TZID=America/Toronto:20201215T130000
DTSTAMP:20260405T185234
CREATED:20201026T180404Z
LAST-MODIFIED:20210108T203414Z
UID:10245-1608033600-1608037200@mbd.ccrm.ca
SUMMARY:Adipose Biology Seminar Series
DESCRIPTION:The adipose tissue is an organ widely distributed throughout the body\, and it is involved in a large variety of medical conditions and metabolic disorders. In recent years\, there has been a growing interest in adipose tissue biology research\, both internationally and locally\, in different departments and institutes. This seminar series serves to facilitate discussion and foster collaborations between PIs and trainees with an interest in adipose tissue research in the Toronto region and beyond. The Adipose Biology Seminar Series is an online monthly meeting in which PIs and trainees will present and discuss novel data pertinent to adipose tissue biology. We aim to host speakers from diverse research foci such as obesity\, diabetes\, cancer and trauma to provide an opportunity to learn about exciting new developments in the field and build connections within a local network. If you are interested in showcasing your work and ideas to the adipose research community\, please contact the meeting organizers. \nTo join this group\, please send an email.
URL:https://mbd.ccrm.ca/event/adipose-biology-seminar-series/
LOCATION:Virtual
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20201207T083000
DTEND;TZID=America/Toronto:20201208T143000
DTSTAMP:20260405T185234
CREATED:20200731T170114Z
LAST-MODIFIED:20210108T203916Z
UID:8684-1607329800-1607437800@mbd.ccrm.ca
SUMMARY:Medicine by Design 5th Annual Symposium
DESCRIPTION:Event Details\nDay 1: Monday\, December 7 — 8:30 a.m. to 2:00 p.m.\nDay 2: Tuesday\, December 8 — 10:30 a.m. to 2:30 p.m.\n*Medicine by Design’s 5th Annual Symposium is a two-day event. Participants will automatically be registered for all sessions. \nMedicine by Design’s 5th Annual Symposium will bring together principal investigators and trainees from across the University of Toronto and its affiliated hospitals\, members of our Scientific Advisory Board\, representatives from our ecosystem partners across industry\, the investment community\, government and the not-for-profit sector\, and international collaborators to advance our research toward impact. \nThe theme of this year’s virtual symposium is Better Science through Convergence. Through talks by invited speakers from across North America and Medicine by Design principal investigators\, we will highlight how collaboration and convergence across research disciplines are accelerating regenerative medicine discoveries and translation. We will also hold a virtual poster session featuring the research of select trainees working on Medicine by Design-funded projects. \nInvited Speakers\n \nGeneral Registration\nGeneral registration is now closed. If you have any questions\, please email info.mbd@utoronto.ca. \nVirtual Poster Session\nThe symposium will feature a virtual poster session to highlight the research taking place in Medicine by Design-funded labs. All attendees are encouraged to browse the posters\, which will be displayed on the virtual platform\, at any time during the symposium. Trainees whose posters are featured in the session will be available to discuss their work on December 7\, from 12:15 p.m. to 2 p.m. \nThe submission period for poster abstracts is now closed. If you have any questions\, please email info.mbd@utoronto.ca. \nAgenda\n Download Agenda
URL:https://mbd.ccrm.ca/event/5th-annual-medicine-by-design-symposium/
LOCATION:Virtual
CATEGORIES:Symposium
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20201130T140000
DTEND;TZID=America/Toronto:20201130T150000
DTSTAMP:20260405T185234
CREATED:20201027T161807Z
LAST-MODIFIED:20201027T161807Z
UID:10266-1606744800-1606748400@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please send an email to find out more about the myogenesis discussion group. \nAbout the Myogenesis Discussion Group\nThe study of myology (skeletal\, smooth and cardiac muscle structure\, function and development) has wide-ranging importance in the field of regenerative medicine. Skeletal muscle is the most abundant tissue in the human body and cardiac muscle is required to circulate blood throughout it. Furthermore\, smooth muscle is present in the walls of hollow organs and the vasculature system\, making these tissues critical for normal physiological function. The goal of this discussion group is to explore models of development\, disease and regeneration in muscle tissues\, as well as potential therapeutic approaches. Within this\, we aim to discuss novel techniques to quantitatively measure all aspects of myology and the challenges associated with developing representative models for these complex tissues.
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-3/
LOCATION:Virtual
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20201117T120000
DTEND;TZID=America/Toronto:20201117T130000
DTSTAMP:20260405T185234
CREATED:20200204T180647Z
LAST-MODIFIED:20201103T223731Z
UID:7803-1605614400-1605618000@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Fei Chen\, PhD - Broad Institute of MIT and Harvard
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Fei Chen\, PhD\, a Schmidt Fellow at the Broad Institute of Harvard University and the Massachusetts Institute of Technology. \nThe title of this talk will be\, “Next generation tools for spatial and temporal genomics” \nClick HERE to register for this virtual event. \n  \n \nMore About Fei Chen: \nFei Chen is currently a core faculty member at the Broad Institute of MIT and Harvard\, and assistant professor at Harvard Stem Cell and Regenerative Biology. He obtained his PhD in biological engineering from the Massachusetts Institute of Technology in 2016. Fei was a Schmidt Fellow at the Broad Institute of MIT and Harvard from 2017-2020. Fei was an Axline scholar at the California Institute of Technology and graduated with a bachelor’s degree in Electrical Engineering in 2011. At the Broad Institute of MIT and Harvard\, his lab sets out pioneer novel tools at the intersection of genomics and microscopy to bridge single-cell genomics with space and time to enable discoveries of where cell types are localized within intact tissues\, when relevant transcriptional modules are active. His awards include the National Institutes of Health Director’s Early Independence Award and the Allen Distinguished Investigator Award.
URL:https://mbd.ccrm.ca/event/global-speaker-series-fei-chen-phd-broad-institute/
LOCATION:Virtual
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
END:VCALENDAR