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DTSTART;TZID=America/Toronto:20230327T140000
DTEND;TZID=America/Toronto:20230327T150000
DTSTAMP:20230117T213458Z
CREATED:20230117T204040Z
LAST-MODIFIED:20230117T213458Z
UID:19385-1679925600-1679929200@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.  \n 
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-16/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230323T100000
DTEND;TZID=America/Toronto:20230323T110000
DTSTAMP:20230125T174258Z
CREATED:20230125T174258Z
LAST-MODIFIED:20230125T174258Z
UID:19454-1679565600-1679569200@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-22/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230320T110000
DTEND;TZID=America/Toronto:20230320T120000
DTSTAMP:20230125T174115Z
CREATED:20230125T174115Z
LAST-MODIFIED:20230125T174115Z
UID:19448-1679310000-1679313600@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-21/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230315T120000
DTEND;TZID=America/Toronto:20230315T130000
DTSTAMP:20230218T194710Z
CREATED:20230104T172944Z
LAST-MODIFIED:20230218T194710Z
UID:19207-1678881600-1678885200@mbd.ccrm.ca
SUMMARY:Careers Beyond Academia
DESCRIPTION:  \nVirtutal event: Register here\nAbout the series“What are you doing after you graduate?” This is one of the biggest questions facing trainees in the life sciences. Stem Cell Network (SCN) and Medicine by Design have partnered to host Careers Beyond Academia\, a virtual career seminar series that will profile a wide variety of different careers available to trainees who hold a degree in the life sciences. The goal of the series is to help trainees understand the different careers available outside of academia\, the skills required for certain positions\, and some of the daily functions of those positions. \nEach session will feature two speaker presentations that will be recorded and available on SCN’s website and YouTube channel. Trainees will be able to participate in a joint Q&A and panel discussion during the session. \nWho should attend? Attendees should be research trainees (graduate students\, post-doctoral fellows\, research associates and/or technicians currently working Canadian labs) who are interested in hearing from professionals working in the life sciences industry and are planning their future career development. Emphasis will be on careers available after a graduate degree (MSc or PhD) in the life sciences\, and particularly in stem cells/regenerative medicine where possible. \nLearning objectives Help trainees understand different careers available outside of academia\, what skills are required for those positions\, and what the daily functions of those positions would typically be Expose candidates to careers that they might not have previously considered as typical careers in the life sciences.
URL:https://mbd.ccrm.ca/event/careers-beyond-academia/
LOCATION:Virtual
CATEGORIES:Career Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230314T130000
DTEND;TZID=America/Toronto:20230314T140000
DTSTAMP:20230222T191147Z
CREATED:20230104T143408Z
LAST-MODIFIED:20230222T191147Z
UID:19172-1678798800-1678802400@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Domitilla Del Vecchio\, PhD – Massachusetts Institute of Technology
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Domitilla Del Vecchio\, PhD\, from the Massachusetts Institute of Technology. \nTalk title: Synthetic genetic circuits to uncover and enforce the OCT4 trajectories of successful reprogramming of human fibroblasts. \nRegister for virtual\nRegister for in-person\nAbout the Del Vecchio lab\n \n \nDomitilla Del Vecchio received the PhD degree in Control and Dynamical Systems from the California Institute of Technology\, Pasadena\, and the Laurea degree in Electrical Engineering (Automation) from the University of Rome at Tor Vergata in 2005 and 1999\, respectively. From 2006 to 2010\, she was an Assistant Professor in the Department of Electrical Engineering and Computer Science and in the Center for Computational Medicine and Bioinformatics at the University of Michigan\, Ann Arbor. In 2010\, she joined the Department of Mechanical Engineering at the Massachusetts Institute of Technology (MIT)\, where she is currently Professor and member of the Synthetic Biology Center. She is a Fellow of the International Federation of Automatic Control (2022)\, an IEEE Fellow (2021)\, and a recipient of the Newton Award for Transformative Ideas during the COVID-19 Pandemic (2020)\, the 2016 Bose Research Award (MIT)\, the Donald P. Eckman Award from the American Automatic Control Council (2010)\, the NSF Career Award (2007)\, the American Control Conference Best Student Paper Award (2004)\, and the Bank of Italy Fellowship (2000). Her research focuses on developing techniques to make synthetic genetic circuits robust to context and on applying these to biosensing and cell fate control for regenerative medicine applications. \n  \nTalk abstract\nReprogramming human fibroblasts to induced pluripotent stem cells (iPSCs) is inefficient\, with heterogeneity among transcription factor (TF) trajectories driving divergent cell states. Nevertheless\, the impact of TF dynamics on reprogramming efficiency remains uncharted. In this work\, we identify the successful reprogramming trajectories of the core pluripotency TF\, OCT4\, and design a genetic controller that enforces such trajectories with high precision. By combining a genetic circuit that generates a wide range of OCT4 trajectories with live cell imaging\, we track OCT4 trajectories with clonal resolution and find that a distinct constant OCT4 trajectory is required for colony formation. We then develop a genetic controller circuit that yields a tight OCT4 distribution around the identified trajectory. In terms of reprogramming efficiency\, this controller outperforms other circuits that less accurately regulate OCT4. Our approach is generalizable for identifying and enforcing TF dynamics for cell fate programming applications.
URL:https://mbd.ccrm.ca/event/global-speaker-series-domitilla-del-vecchio-phd/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230227T140000
DTEND;TZID=America/Toronto:20230227T150000
DTSTAMP:20230117T213520Z
CREATED:20230117T203946Z
LAST-MODIFIED:20230117T213520Z
UID:19383-1677506400-1677510000@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.  \n 
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-24/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230223T130000
DTEND;TZID=America/Toronto:20230223T140000
DTSTAMP:20230206T185723Z
CREATED:20220714T012204Z
LAST-MODIFIED:20230206T185723Z
UID:17688-1677157200-1677160800@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Jeff Biernaskie\, PhD – University of Calgary
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Jeff Biernaskie\, PhD\, from the University of Calgary. \nTalk title: Insights into the determinants of tissue regeneration versus scar formation. \nThis is a hybrid event. Register for the in-person or virtual option. Lunch will be served to in-person registrants. \nThis event is also being sponsored by the Collaborative Specialization in Developmental Biology. \nRegister now for virtual\nRegister now for in-person  \nAbout the Biernaskie lab\n \n \nDr. Biernaskie completed his BSc in Neuroscience at the University of Lethbridge. He earned a PhD in Neuroscience at Memorial University studying the effects of focused rehabilitative experience on brain plasticity following stroke. He completed postdoctoral training with Freda Miller and David Kaplan studying skin and neural stem cell biology at the Hospital for Sick Children in Toronto. In 2009\, he joined the Faculty of Veterinary Medicine at the University of Calgary\, where is he currently a Professor in Stem Cell Biology and Regenerative Medicine. He is a member of the Alberta Children’s Hospital Research Institute and the Hotchkiss Brain Institute and he holds the Calgary Firefighters Burn Treatment Society Chair in Skin Regeneration and Wound Healing. In 2019\, he was elected as a member of the Royal Society of Canada\, College of Scholars\, Artists and Scientists. \nHis research program is focused on understanding the cellular and molecular mechanisms that promote fibrotic versus regenerative healing with the goal of developing treatments to restore organ function following injury or disease. His group is also interested in how skin and brain stem/progenitor cells are regulated during homeostasis and how factors like injury\, advanced aging and the immune system impact their function. \nTalk abstract\nAdult mammals have evolved to heal deep skin wounds by forming fibrotic scar in order to most efficiently fill the defect and support reepithelialisation to prevent infection. But it is unclear as to the mechanisms that drive this propensity and whether there are ways to re-awaken pro-regenerative processes in order to better restore normal function to the healed skin. I will describe our work in captive adult reindeer which provides a powerful comparative model of scarless versus fibrotic skin wound healing. Full-thickness injuries of reindeer antler skin (velvet) exhibit near-complete regeneration\, whereas back skin forms fibrotic scar. By employing single-cell multi-omics we found that even prior to injury\, velvet demal fibroblasts exhibit a transcriptional ground state that resembles human fetal fibroblasts\, whereas back skin fibroblasts express inflammatory mediators mimicking pro-fibrotic adult human and rodent fibroblasts. As a consequence of these distinct resting states\, skin injury elicited site-specific immune responses: back skin fibroblasts amplifying myeloid infiltration and maturation\, whereas velvet fibroblasts adopted an immunosuppressive phenotype that restricted leukocyte recruitment and hastened immune resolution. Finally\, I will describe additional experiments that highlight a critical role for fibroblasts in orchestrating local immune function during wound healing and that decoupling these fibroblast-immune interactions may be a promising approach to mitigate scar.
URL:https://mbd.ccrm.ca/event/global-speaker-series-feb-2023/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230222T110000
DTEND;TZID=America/Toronto:20230222T120000
DTSTAMP:20230125T173321Z
CREATED:20230125T173321Z
LAST-MODIFIED:20230125T173321Z
UID:19449-1677063600-1677067200@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-20/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230216T120000
DTEND;TZID=America/Toronto:20230216T130000
DTSTAMP:20230104T172528Z
CREATED:20230104T171450Z
LAST-MODIFIED:20230104T172528Z
UID:19200-1676548800-1676552400@mbd.ccrm.ca
SUMMARY:Careers Beyond Academia: Jodi Garner\, Roche\, & Patrycja Thompson\, University of Toronto
DESCRIPTION:Speakers Jodi Garner\, PhD Strategic Collaborations Lead\, Roche Patrycja Thompson\, PhD Partnerships Officer\, Strategic Initiatives Industry Partnerships\, University of Toronto \nVirtual Event – Register Here\nAbout the series“What are you doing after you graduate?” This is one of the biggest questions facing trainees in the life sciences. Stem Cell Network (SCN) and Medicine by Design have partnered to host Careers Beyond Academia\, a virtual career seminar series that will profile a wide variety of different careers available to trainees who hold a degree in the life sciences. The goal of the series is to help trainees understand the different careers available outside of academia\, the skills required for certain positions\, and some of the daily functions of those positions. \nEach session will feature two speaker presentations that will be recorded and available on SCN’s website and YouTube channel. Trainees will be able to participate in a joint Q&A and panel discussion during the session. \nWho should attend? Attendees should be research trainees (graduate students\, post-doctoral fellows\, research associates and/or technicians currently working Canadian labs) who are interested in hearing from professionals working in the life sciences industry and are planning their future career development. Emphasis will be on careers available after a graduate degree (MSc or PhD) in the life sciences\, and particularly in stem cells/regenerative medicine where possible. \nLearning objectives Help trainees understand different careers available outside of academia\, what skills are required for those positions\, and what the daily functions of those positions would typically be Expose candidates to careers that they might not have previously considered as typical careers in the life sciences.
URL:https://mbd.ccrm.ca/event/careers-beyond-academia-jodi-garner-roche-patrycja-thompson-university-of-toronto/
LOCATION:Virtual
CATEGORIES:Career Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230214T153000
DTEND;TZID=America/Toronto:20230214T163000
DTSTAMP:20230206T174817Z
CREATED:20230203T203418Z
LAST-MODIFIED:20230206T174817Z
UID:19503-1676388600-1676392200@mbd.ccrm.ca
SUMMARY:Healthy & Inclusive Labs Trainee Town Hall
DESCRIPTION:What makes a healthy lab environment? What can be done to better support you as a trainee? Share your thoughts at the Healthy & Inclusive Labs Trainee Town Hall! \nJoin us for a crucial town hall discussion on the challenges impacting the social health of your lab. We want to hear your perspective on what could be done to create lab environments that better support equity\, diversity and inclusion\, mental health\, and overall performance. Your feedback will help Medicine by Design’s Healthy and Inclusive Labs Committee develop more effective and relevant event programming. \n  \nRegister now\n  \nTo help guide our discussions at the town hall\, we ask that you fill out this survey. We would love to have your input even if you can’t attend!
URL:https://mbd.ccrm.ca/event/healthy-incl-labs-town-hall/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Healthy & Inclusive Labs
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230130T140000
DTEND;TZID=America/Toronto:20230130T150000
DTSTAMP:20230117T213533Z
CREATED:20230117T203858Z
LAST-MODIFIED:20230117T213533Z
UID:19381-1675087200-1675090800@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.  \n 
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-25/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230126T140000
DTEND;TZID=America/Toronto:20230126T150000
DTSTAMP:20230120T180222Z
CREATED:20230104T163518Z
LAST-MODIFIED:20230120T180222Z
UID:18141-1674741600-1674745200@mbd.ccrm.ca
SUMMARY:Conversations in Convergence: Targeting protein membranes in disease
DESCRIPTION:Join us for our Conversations in Convergence series\, which features interactive discussions between Medicine by Design researchers who study similar questions using different approaches. \nRegister now\n\nSpeakers \nVineeth Raveendran\, PhD Candidate\, Melanie Woodin lab\, Department of Cell & Systems Biology\, University of Toronto \nEnhancing potassium-chloride cotransporter-2 (KCC2) function in neurons by targeting protein-protein interactions \nVineeth Raveendran is a PhD candidate in Melanie Woodin’s lab and is working on enhancing potassium-chloride cotransporter-2 (KCC2) function in neurons by targeting protein-protein interactions (PPI). Vineeth graduated from the Indian Institute of Science Education and Research-Kolkata (IISER-K) with a Bachelor of Science-Master of Science (BS-MS) dual degree\, majoring in Biological Sciences. His master’s degree research focused on the role of gap junction proteins (connexins) in maintaining neural homeostasis and myelination. In the Woodin Lab\, he has validated PPI inhibitor peptides that can increase KCC2 expression and function\, which is essential for maintaining synaptic inhibition in adult neurons. \n\nMichael Garton\, Assistant Professor\, Institute of Biomedical Engineering\, University of Toronto\, and Canada Research Chair\, Synthetic Biology. \nOvercoming barriers to integrating synthetic biology with regenerative medicine\n \nMichael Garton is an Assistant Professor in the Institute of Biomedical Engineering at the University of Toronto and the Canada Research Chair in synthetic biology. He completed his undergraduate education in chemistry and PhD in computational biology at the University of Nottingham\, U.K. He then moved to Canada for postdoctoral fellowships at The Hospital for Sick Children and University of Toronto\, which allowed him to develop expertise in protein design. He set up his own lab in 2019\, focused on protein design in the context of cell and gene therapy. \n\nAbout Conversations in Convergence\n\nThe goal is to foster cross-disciplinary discussions in support of convergence\, which is the integration of approaches from engineering\, science\, medicine and other fields to expand knowledge and spark innovation. The researchers will discuss how their unique perspectives\, knowledge and ideas inform their work\, and how their diverse approaches intersect and complement one another to advance regenerative medicine. \n 
URL:https://mbd.ccrm.ca/event/conversations-in-convergence/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Other Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230119T113000
DTEND;TZID=America/Toronto:20230119T123000
DTSTAMP:20230125T173234Z
CREATED:20230125T173234Z
LAST-MODIFIED:20230125T173234Z
UID:19450-1674127800-1674131400@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-19/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230118T120000
DTEND;TZID=America/Toronto:20230118T130000
DTSTAMP:20230105T185949Z
CREATED:20230104T165317Z
LAST-MODIFIED:20230105T185949Z
UID:19192-1674043200-1674046800@mbd.ccrm.ca
SUMMARY:Careers Beyond Academia: Helen Luck\, Shift Health\, & Ryan Mitchell\, Satellos Bioscience Inc.
DESCRIPTION:Speakers Helen Luck\, PhD\, Senior Consultant\, Shift Health Ryan Mitchell\, PhD\, Director\, Business Development\, Satellos Bioscience Inc. \nVirtual Event – Register Here\nAbout the series“What are you doing after you graduate?” This is one of the biggest questions facing trainees in the life sciences. Stem Cell Network (SCN) and Medicine by Design have partnered to host Careers Beyond Academia\, a virtual career seminar series that will profile a wide variety of different careers available to trainees who hold a degree in the life sciences. The goal of the series is to help trainees understand the different careers available outside of academia\, the skills required for certain positions\, and some of the daily functions of those positions. \nEach session will feature two speaker presentations that will be recorded and available on SCN’s website and YouTube channel. Trainees will be able to participate in a joint Q&A and panel discussion during the session. \nWho should attend? Attendees should be research trainees (graduate students\, post-doctoral fellows\, research associates and/or technicians currently working Canadian labs) who are interested in hearing from professionals working in the life sciences industry and are planning their future career development. Emphasis will be on careers available after a graduate degree (MSc or PhD) in the life sciences\, and particularly in stem cells/regenerative medicine where possible. \nLearning objectives Help trainees understand different careers available outside of academia\, what skills are required for those positions\, and what the daily functions of those positions would typically be Expose candidates to careers that they might not have previously considered as typical careers in the life sciences.
URL:https://mbd.ccrm.ca/event/careers-beyond-academia-jan-2023/
LOCATION:Virtual
CATEGORIES:Career Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230117T120000
DTEND;TZID=America/Toronto:20230117T130000
DTSTAMP:20230118T213640Z
CREATED:20220714T013546Z
LAST-MODIFIED:20230118T213640Z
UID:17674-1673956800-1673960400@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Matthias Lutolf\, PhD – École Polytechnique Fédérale de Lausanne
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. \nMedicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Matthias Lutolf\, PhD\, from the École Polytechnique Fédérale de Lausanne to give a talk titled\, “Engineering Organoid Development.” This event will be virtual. \nRegister now\n\nAbout the Lutolf lab \nMatthias Lutolf is Professor of Bioengineering at the Swiss Federal Institute of Technology Lausanne (EPFL) and founding Director of the Roche Institute for Translational Bioengineering. His research focuses on the development of advanced bioengineering strategies to produce next-generation organoids with improved reproducibility and physiological relevance for basic research and real-world applications in drug discovery and precision medicine. For example\, he pioneered the generation of organoids in fully controllable hydrogel matrices and novel approaches to control organoid patterning and morphogenesis through microfluidics\, bioprinting\, and microfabrication. \nTalk abstract: Engineering Organoid Development\nOrganoids form through poorly understood morphogenetic processes in which initially homogeneous ensembles of stem cells spontaneously self-organize in suspension or within permissive three-dimensional extracellular matrices. Yet\, the absence of virtually any predefined patterning influences such as morphogen gradients or mechanical cues results in an extensive heterogeneity. Moreover\, the current mismatch in shape\, size and lifespan between native organs and their in vitro counterparts hinders their even wider applicability. In this talk\, Matthias Lutolf will discuss some of his ongoing efforts in developing next-generation organoids that are assembled by guiding cell-intrinsic self-patterning through engineered stem cell microenvironments. \nLearn more
URL:https://mbd.ccrm.ca/event/global-speaker-series-jan-2023/
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;VALUE=DATE:20221208
DTEND;VALUE=DATE:20221209
DTSTAMP:20220711T192217Z
CREATED:20220711T192217Z
LAST-MODIFIED:20220711T192217Z
UID:17419-1670457600-1670543999@mbd.ccrm.ca
SUMMARY:Medicine by Design 7th Annual Symposium
DESCRIPTION:QUICK LINKS: EVENT DETAILS AND AGENDA  |  ABOUT THE SYMPOSIUM | REGISTRATION  |  POSTER SESSION\n\nEvent Details and Agenda\nEvent date/time: Thursday\, December 8 — 8:15 a.m. to 5:30 p.m.\n\n\nFull symposium agenda tbc.\n\n\nAbout the Symposium\nJoin us for the seventh annual Medicine by Design symposium. The symposium will bring together principal investigators and trainees from across the University of Toronto and its affiliated hospitals\, along with industry partners\, the investment community\, government\, the not-for-profit sector and international collaborators. The theme of this year’s symposium is\, “Grand Questions in Regenerative Medicine.” \nWe will also hold a poster session featuring the research of select trainees working on Medicine by Design-funded projects. \nRegistration Opens in September\nTOP\n\nInvited Speakers\n\nAviv Regev\, PhD\, Head\, Executive Vice President\, Genentech Research and Early Development\, Roche\nThomas Rando\, MD\, PhD\, Director\, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research\, University of California\, Los Angeles\nSamantha Morris\, PhD\, Associate Professor\, Department of Developmental Biology\, Washington University School of Medicine\nKarmella Haynes\, PhD\, Associate Professor\, Wallace H. Coulter Department of Biomedical Engineering\, Georgia Institute of Technology and Emory University\nCliona Rooney\, PhD\, Professor\, Department of Pediatrics\, Section of Hematology-Oncology\, Baylor College of Medicine\n\nTOP\n\nGeneral Registration\nSpace is limited. Registration will be open early September.  If you have any questions\, please email info.mbd@utoronto.ca. \nTOP\n\n Poster Session\nThe symposium will feature an in-person poster session to highlight the innovative research taking place in Medicine by Design-funded labs. The submission period will open in early September. Those who have been selected will be contacted via email with next steps in October. \nIf you have any questions regarding the poster submission process\, please contact our Scientific Manager\, Angela Zhou at angela.zhou@utoronto.ca. \nAll attendees are encouraged to browse the posters\, which will be displayed all day during the symposium. Trainees whose posters are featured in the session will be available to discuss their work on December 8\, between 11:35 a.m. to 1:00 p.m. \nTOP
URL:https://mbd.ccrm.ca/event/7th-annual-symposium/
LOCATION:MaRS Auditorium\, 101 College Street\, Toronto\, Ontario\, M5G 1L7\, Canada
CATEGORIES:Symposium
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221129T120000
DTEND;TZID=America/Toronto:20221129T130000
DTSTAMP:20230102T191449Z
CREATED:20220322T175344Z
LAST-MODIFIED:20230102T191449Z
UID:16814-1669723200-1669726800@mbd.ccrm.ca
SUMMARY:Adipose Biology Seminar Series
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/adipose-biology-seminar-series-17/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221128T140000
DTEND;TZID=America/Toronto:20221128T150000
DTSTAMP:20221219T154140Z
CREATED:20220322T171729Z
LAST-MODIFIED:20221219T154140Z
UID:16795-1669644000-1669647600@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.  \n 
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-14/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221124T113000
DTEND;TZID=America/Toronto:20221124T123000
DTSTAMP:20220330T211005Z
CREATED:20220330T211005Z
LAST-MODIFIED:20220330T211005Z
UID:16860-1669289400-1669293000@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-18/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221116T120000
DTEND;TZID=America/Toronto:20221116T130000
DTSTAMP:20230102T191623Z
CREATED:20220714T163428Z
LAST-MODIFIED:20230102T191623Z
UID:17730-1668600000-1668603600@mbd.ccrm.ca
SUMMARY:Beyond Academia - Catia Perciani\, PhD Medical Scientist – HIV\, Gilead Sciences and Nikta Fay\, PhD Key Account Executive – Cell Culture\, STEMCELL Technologies
DESCRIPTION:About the seriesTo what extent can we plan and design our careers? How much depends on our environment\, the choices we make\, the opportunities that present themselves\, the networks we build\, and the achievements and failures we experience along the way? Medicine by Design and Stem Cell Network have partnered to host Careers Beyond Academia\, a virtual career seminar series that will profile a wide variety of different careers available to trainees who hold a degree in the life sciences. The goal of the series is to help trainees understand the different careers available outside of academia\, the skills required for certain positions\, and some of the daily functions of those positions. \nVirtual Event – Register Here\nSpeakers: \n\nCatia Perciani\, PhD Medical Scientist – HIV\, Gilead Sciences\nNikta Fay\, PhDKey Account Executive – Cell Culture\, STEMCELL Technologies\n\nEach session will feature two speaker presentations that will be recorded and available on both Medicine by Design and Stem Cell Network’s website and YouTube channel. Trainees will be able to participate in a joint Q&A and panel discussion during the session. \n 
URL:https://mbd.ccrm.ca/event/beyond-academia-speaker-tbc/
LOCATION:Virtual
CATEGORIES:Career Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221110T120000
DTEND;TZID=America/Toronto:20221110T130000
DTSTAMP:20221026T204249Z
CREATED:20220627T132515Z
LAST-MODIFIED:20221026T204249Z
UID:17497-1668081600-1668085200@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Martin Fussenegger\, PhD – ETH Zurich
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Martin Fussenegger\, PhD\, Professor\, Department of Biosystems Science and Engineering\, ETH Zurich. The title of this talk will be\, “Toward A World of ElectroGenetics” \nIn Person – Register Here\nVirtual – Register Here\nHybrid event\, with in-person and virtual options\n\nIn-person will be held at the Terrence Donnelly Centre for Cellular & Biomolecular Research\, Red Room.\nVirtual event links will be sent after registration.\n\nMORE ABOUT MARTIN FUSSENEGGER: \n \nMartin Fussenegger is Professor of Biotechnology and Bioengineering at the Department of Biosystems Science and Engineering (D-BSSE) of the ETH Zurich in Basel as well as at the University of Basel.His research focuses on mammalian cell engineering\, in particular on the assembly of synthetic gene circuits that process complex control and closed-loop expression logic as well as on the production of theranostic designer cell implants that interface with host metabolism to correct prominent metabolic disorders. \nMartin Fussenegger graduated with Werner Arber at the Biocenter of the University of Basel (1992)\, obtained his Ph.D. in Medical Microbiology (1994) at the Max Planck Institute of Biology (Tübingen\, Germany) and continued his postdoctoral studies on host-pathogen interactions at the Max Planck Institute of Infection Biology (Berlin\, 1995). He then joined the ETH Institute of Biotechnology (1996)\, where he received his habilitation in 2000\, and became Swiss National Science Foundation Professor of Molecular Biotechnology in 2002\, prior to being awarded a Chair in Biotechnology and Bioengineering at the ETH Institute for Chemical and Bioengineering in 2004. \nMartin Fussenegger received the Gaden Award\, the Merck Cell Culture Engineering Award\, the Medal of the European Society for Animal Cell Technology (ESACT)\, the Gutenberg Chair Excellence Award\, the James E. Bailey Award and two consecutive Advanced Grant Awards of the European Research Council. \n Learn more about Martin Fussenegger
URL:https://mbd.ccrm.ca/event/global-speaker-series-martin-fussenegger-phd-eth-zurich-2/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221110T113000
DTEND;TZID=America/Toronto:20221110T123000
DTSTAMP:20220330T210935Z
CREATED:20220330T210935Z
LAST-MODIFIED:20220330T210935Z
UID:16873-1668079800-1668083400@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-17/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221103T150000
DTEND;TZID=America/Toronto:20221103T163000
DTSTAMP:20221027T150643Z
CREATED:20221019T190417Z
LAST-MODIFIED:20221027T150643Z
UID:18682-1667487600-1667493000@mbd.ccrm.ca
SUMMARY:Program Information Session: Building a Biotech Venture 2023
DESCRIPTION:Join us on November 3 for an information session to learn about the Building a Biotech Venture Program.\nRegister for the info session\nTake your first steps toward entrepreneurship with the Building a Biotech Venture program\, a program for trainees who are doing regenerative medicine- or precision medicine-related research in labs at the University of Toronto or its affiliated hospitals. \nMedicine by Design is offering this program in partnership with Precision Medicine Initiative (PRiME) as well as our foundational partners the Health Innovation Hub (H2i)\, a campus-linked accelerator at the Temerty Faculty of Medicine; and Talk Boutique. \nThrough a series of workshops over winter/spring 2023\, teams will\n-Learn how to think about their research in terms of a product or business;\n-Build a business canvas and develop their product or venture concept;\n-Receive guidance from industry experts on intellectual property\, clinical translation\, and early-stage stage investment.\n-Create a pitch deck and receive coaching on telling their venture story; and\n-Receive regular mentoring from entrepreneurs throughout the process. \nThe program will culminate in a pitch competition in April 2023\, where the first-place team will receive $25\,000 in research funding to advance their product concept.\n \nProgram Information Session and Networking\nNovember 3\, 3 p.m. to 4:30 p.m.\nThe information session will provide an overview of the program and an introduction to H2i’s 10-point plan\, which outlines 10 key elements of a business canvas. Completing a business canvas is a component of the program application. The session will be followed by networking where you can meet like-minded trainees to form your team. \n\nBuilding a Biotech Venture program breakdown:\n\nThe Building a Biotech Venture Program occurs in two phases: \nVenture Development (January-March 2022)– Ten teams will develop their ventures with guidance and training through mentorship and workshop programing. Workshops will be run by industry experts to help in scaling their ventures and prepare them for the pitch competition.\nWorkshop 1: Mentor introduction event (January)\nWorkshop 2: Intellectual property (January)\nWorkshop 3: Clinical translation and regulatory affairs (February)\nWorkshop 4: Early-stage investment (February)\nWorkshop 5: Pitching and presentation skills workshop (March) \nPitch Competition – Teams will receive pitch coaching\, and compete in a pitch competition to a panel of industry experts. Teams accepted into the Venture Development phase of the program are eligible to participate in the Pitch Development phase but will need to submit a separate application once it opens in late February. Select teams will pitch for a chance to receive $25\,000 in research funding.
URL:https://mbd.ccrm.ca/event/info-session-biotech-venture-2023/
LOCATION:ONRamp\, 100 College St\, Suite 150\, Toronto\, M5G 1L5\, Canada
CATEGORIES:Partner Events,Workshops
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221031T140000
DTEND;TZID=America/Toronto:20221031T150000
DTSTAMP:20220322T171545Z
CREATED:20220322T171518Z
LAST-MODIFIED:20220322T171545Z
UID:16796-1667224800-1667228400@mbd.ccrm.ca
SUMMARY:Myogenesis Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/myogenesis-discussion-group-13/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221027T113000
DTEND;TZID=America/Toronto:20221027T123000
DTSTAMP:20220329T182751Z
CREATED:20220329T182751Z
LAST-MODIFIED:20220329T182751Z
UID:16862-1666870200-1666873800@mbd.ccrm.ca
SUMMARY:Modelling Cell Development & Regeneration Discussion Group
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/modelling-cell-development-regeneration-discussion-group-16/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221025T120000
DTEND;TZID=America/Toronto:20221025T130000
DTSTAMP:20220322T175316Z
CREATED:20220322T175316Z
LAST-MODIFIED:20220322T175316Z
UID:16815-1666699200-1666702800@mbd.ccrm.ca
SUMMARY:Adipose Biology Seminar Series
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/adipose-biology-seminar-series-16/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221018T120000
DTEND;TZID=America/Toronto:20221018T130000
DTSTAMP:20221011T130800Z
CREATED:20220627T132215Z
LAST-MODIFIED:20221011T130800Z
UID:17500-1666094400-1666098000@mbd.ccrm.ca
SUMMARY:Global Speaker Series: Jacob Hanna\, MD\, PhD -Weizmann Institute of Science
DESCRIPTION:The Medicine by Design Global Speaker Series invites established and emerging international leaders in regenerative medicine to engage with our extraordinary community of researchers and clinicians. Medicine by Design\, in partnership with the McEwen Stem Cell Institute\, is pleased to welcome Jacob Hanna\, MD\, PhD\, Senior Scientist and Professor\, Department of Molecular Genetics\, Weizmann Institute of Science. The title of this talk will be\, “Synthetic Ex Utero Embryogenesis: from Naive Pluripotent Stem Cells to Advanced Whole Embryos”. \nIn Person – Register Here \nVirtual – Register Here\nHybrid event\, with in-person and virtual options\n\nIn-person will be held at the Terrence Donnelly Centre for Cellular & Biomolecular Research\, Red Room.\nVirtual event links will be sent after registration.\n\nMORE ABOUT JACOB HANNA: \nBorn in Rama\, an Arab Palestinian village in the Galilee region of Israel\, Professor Jacob (Yaqub) Hanna earned his BSc in medical science\, PhD in immunology\, and MD in clinical medicine summa cum laude from the Hebrew University of Jerusalem. He conducted postdoctoral research at the Whitehead Institute for Biomedical Research at MIT. He joined the department of Molecular Genetics at the Weizmann Institute in 2011. \nProfessor Hanna is pioneering techniques in induced naïve pluripotency from adult cell and synthetic whole embryo models made solely from stem cells ex utero. Professor Hanna was the lead researcher in a study that showed how further-modified iPS cells could be used to treat sickle-cell anemia in mice\, the first proof of concept of the therapeutic application of iPS cells. \nDuring his postdoctoral work\, Professor Hanna received a prestigious Novartis Fellowship from the Helen Hay Whitney Foundation. In 2010\, he was awarded the Sir Charles Clore Prize for Outstanding Appointment in the Weizmann Institute. He received an EMBO Young Investigator Award (2012)\, a Rappaport Prize in biomedical research (2013)\, a Krill Prize by the Wolf Foundation (2013)\, and the Helen and Martin Kimmel Award for Innovative Investigation (2014). In 2014\, he was featured among “40 under 40” innovative scientists by the prestigious journal Cell and was elected as a member of EMBO in 2018. In 2021\, he ranked at the top of the list of 50 leading world thinkers by Prospect magazine. \n Learn more about Jacob (Yaqub) Hanna
URL:https://mbd.ccrm.ca/event/global-speaker-series-jacob-hanna-phd-weizmann-institute-of-science/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Global Speaker Series
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221013T120000
DTEND;TZID=America/Toronto:20221013T130000
DTSTAMP:20220816T213015Z
CREATED:20220714T163511Z
LAST-MODIFIED:20220816T213015Z
UID:17726-1665662400-1665666000@mbd.ccrm.ca
SUMMARY:Beyond Academia - Betty Zou\, PhD Research and Communications Specialist\, University of Toronto and Adriana Suarez-Gonzalez\, PhD Science and Technology Advisor\, 10X Genomics
DESCRIPTION:About the series \nTo what extent can we plan and design our careers? How much depends on our environment\, the choices we make\, the opportunities that present themselves\, the networks we build\, and the achievements and failures we experience along the way? Medicine by Design and Stem Cell Network have partnered to host Careers Beyond Academia\, a virtual career seminar series that will profile a wide variety of different careers available to trainees who hold a degree in the life sciences. The goal of the series is to help trainees understand the different careers available outside of academia\, the skills required for certain positions\, and some of the daily functions of those positions. \n Virtual Event – Register Here\nSpeakers:\n\nBetty Zou\, PhDResearch and Communications Specialist\, University of Toronto\nAdriana Suarez-Gonzalez\, PhDScience and Technology Advisor\, 10X Genomics\n\nEach session will feature two speaker presentations that will be recorded and available on both Medicine by Design and Stem Cell Network’s website and YouTube channel. Trainees will be able to participate in a joint Q&A and panel discussion during the session. \n 
URL:https://mbd.ccrm.ca/event/beyond-academia-speaker-tbc-2/
LOCATION:Virtual
CATEGORIES:Career Speaker Series
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220929T150000
DTEND;TZID=America/Toronto:20220929T160000
DTSTAMP:20220921T201635Z
CREATED:20220817T163705Z
LAST-MODIFIED:20220921T201635Z
UID:18120-1664463600-1664467200@mbd.ccrm.ca
SUMMARY:Conversations in Convergence: Kristin Hope\, PhD\, and Roshane Frances\, PhD
DESCRIPTION:Note: We are excited to transition Conversations in Convergence from a virtual to an in-person event\, providing more opportunity for networking and potential collaboration.  \nJoin us for our Conversations in Convergence series\, which features interactive discussions between Medicine by Design researchers who study similar questions using different approaches. \nThe theme of this conversation will be\, Targeted approaches to improving cell function for therapy. \nRegister Now \n \nSpeakers \nKristin Hope\, PhDSenior Scientist\, Princess Margaret Cancer Centre\, University Health Network\, and Associate Professor\, Department of Medical Biophysics\, University of Toronto  \nHarnessing post-transcriptional circuitries to maximize the therapeutic potential of hematopoietic stem cells \nKristin Hope obtained her PhD from the University of Toronto studying leukemic stem cells in the department of Molecular and Medical Genetics and followed this with a Post-doctoral Fellowship in stem cell functional genetics at the Université de Montreal. Dr. Hope began her independent research program as an Assistant Professor at McMaster University in 2010 and was recruited in 2020 by the Princess Margaret Cancer Centre\, University Health Network where she is a Senior Scientist and holds an Associate Professorship in the Department of Medical Biophysics at the University of Toronto. Dr. Hope also holds an Ontario Institute for Cancer Research Investigator Award and is a Medicine by Design Investigator. \n \n  \nRoshane Frances\, PhD Postdoctoral Research Fellow\, Keith Pardee lab\, Department of Pharmaceutical Sciences\, University of Toronto  \nTCR-CAR T cells: Engineering immune cells to treat cancer \nRoshane Frances is a recent SickKids PhD graduate currently working as a post-doctoral fellow in Dr. Pardee’s Lab at the University of Toronto. During her PhD\, she explored how the embryonic stomach develops in mice and used these insights to study gastric cancer initiation. Wanting to explore more translation specific opportunities\, her post-doctoral studies involved engineering drug-secreting bacteria for the treatment of inflammatory bowel diseases and CAR T-cells to target colon cancer cells! \n \nAbout Conversations in Convergence\n\nThe goal is to foster cross-disciplinary discussions in support of convergence\, which is the integration of approaches from engineering\, science\, medicine and other fields to expand knowledge and spark innovation. The researchers will discuss how their unique perspectives\, knowledge and ideas inform their work\, and how their diverse approaches intersect and complement one another to advance regenerative medicine. \n 
URL:https://mbd.ccrm.ca/event/conversations-in-convergence-kristin-hope-phd-and-roshane-frances-phd/
LOCATION:Donnelly Centre for Cellular and Biomolecular Research\, Red Room\, 160 College Street\, Toronto\, Ontario\, M5S 3E1\, Canada
CATEGORIES:Other Events
ORGANIZER;CN="Medicine by Design":MAILTO:info.mbd@utoronto.ca
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220927T120000
DTEND;TZID=America/Toronto:20220927T130000
DTSTAMP:20220322T175137Z
CREATED:20220322T175137Z
LAST-MODIFIED:20220322T175137Z
UID:16812-1664280000-1664283600@mbd.ccrm.ca
SUMMARY:Adipose Biology Seminar Series
DESCRIPTION:Please visit the discussion groups page for more information.
URL:https://mbd.ccrm.ca/event/adipose-biology-seminar-series-15/
LOCATION:Online
CATEGORIES:Discussion Groups
END:VEVENT
END:VCALENDAR